2Garlick PB, D aries MJ, H earse DJ, et al. Directd etection of free radicals in the reperfused rat heart using electron spin resonancespectroscopy. Circ Res JT - Circulation research, 1987,61:57 -60.
3Muri KW,Lees KR.Clinical experience with excitatory amino acid antagonist[J].Stroke,1995,26:503-513.
4Watanbe T,Yuki S,Egawa M,et al.Protective effects MCI-186 on cerebral ischenia:Possible involvent of free radical scavenging and antioxdant actions[J].J Phat Exp Ther,1994,268:597-604.
5Abe K,Yuki S,Kogure K.Strong attenuation of ische mic and posteschemic brain in rats by a novel free radical scavenger[J].Stroke,1988,19:480-485.
6Nishi H,Watanabe T,Sakurai H,et al.Effetct of MCI-186 on vrain edema in rats[J].Stroke,1989,20:1236-1240.
7横田慎一 熊毅雄治 内海光朝.A Pharmacokinetic Study of MCI—186,a novel drug for cerebrovascular disease in elderly and young healthy subjects[J].临床药理,1997,28(3):693-702.
8Mizuno A,Umemura K,Nakashima M.Inhibitory effect MCI-186,a free radical scavenger,on cerebral ischemia following rat middle cerebral artery occlusion[J].Gen Pharmacol,1998,30(4)∶575-578.
9Kawai H,Nakai H,Misao S,et al.Effects of a novel free radical scavenger,MCI-186,on ischemic brain damage in the rat distal middle cerebral artery occlusion model[J].J Pharmacol Exp Ther,1997,281(2)∶921-927.
