期刊文献+

脑肿瘤与神经元特异性烯醇化酶的相关性研究

下载PDF
导出
摘要 目的观察脑肿瘤患者手术前和手术后神经元特异性烯醇化酶(NSE)[1]的含量变化,探讨其表达变化在脑肿瘤手术前后不同时期的临床意义。方法治疗组分别于手术前、手术后第7天、手术后第21天空腹静脉采集血液标本。用电化学发光法测NSE含量。结果治疗组手术前后各时间的NSE均高于健康对照组,与对照组比较,差异有统计学意义(P【0.01)。NSE手术前含量与手术后第7天、21天比较,差异有统计学意义(P【0.01),手术后第7d与第21d含量比较,无统计学意义(P】0.05)。结论脑肿瘤患者血清NSE水平手术前显著升高。手术后NSE含量较手术前逐渐下降。测定血浆NSE含量有助于脑肿瘤患者的早期诊断和预后判断,具有重要的临床价值。
作者 司长风
出处 《中国保健营养(下半月)》 2013年第7期1646-1646,共1页 China Health Care & Nutrition
  • 相关文献

参考文献4

  • 1袁学谦,肖波,胡珏,王康,吴海香.脑出血急性期神经元特异性烯醇化酶的变化及临床研究[J].中风与神经疾病杂志,2004,21(2):107-108. 被引量:8
  • 2Schaarschmidt H,Prange HW,Reilber H.Neuron-specific enolase concentration in blood as aprognostic parameter in cerebro vascular disease[].Stroke.1994
  • 3Jacobi C,Reiber H.Clinical relevance of increased neuron specific enolase concentration in cerebrospinal fluid[].Clin Chi m Acta.1998
  • 4Wang CD,Zhang ZF,Zhang ZX,et al.Association of release pattern of ser-um neuron-specific enolase with outcome in patients with severe head in-jury[].(J Chin Med Neurosurg).2001

二级参考文献6

  • 1Vermuyten K,Lowenthal A,Karcher D.Detection of neuron specific enolase concentrations in cerebrospinal fluid from patients with neurological disorders by means of a sensitive enzyme immunoassay[J].Clinical Chemical Acta,1990,28(187):69-78.
  • 2Rabinowicz AL,Correale JD,Bracht KA,et al.Neuron-specific enolase is increased after nonconvulsive status epilepticus[J].Epilepsia,1995,36(5):475-479.
  • 3DeGiorgio CM,Tomiyasu U,Gott PS,et al.Hippocampal pyramidal cell loss in human status epilepticus[J].Epilepsia,1992,33(1):23-27.
  • 4Cavazos JE,Das I,Sutula TP.Neuronal loss induced in limbic pathways by kindling:evidence for induction of hippocampal sclerosis by repeated brief seizures[J].J Neurosci,1994,14(5):3106-3121.
  • 5Marangos PJ,Parma AM,Goodwin FK.Functional properties of neuronal and glial isoenzymes of brain enolase[J].J Neurochem,1978,31(3):727-732.
  • 6Hatfield RH,McKernan RM.CSF neuron-specific enolase as a quantitative marker of neuronal damage in a rat stroke model[J].Brain Res,1992,577(2):249-252.

共引文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部