布托啡诺复合右美托咪定用于剖宫产术后镇痛的临床研究

Clinical Study on the Analgesic Effect of Bhutto Butorphanol Combined with Dexmedetomidine in Cesarean Section

目的了解采用剖宫产方式分娩的产妇用布托啡诺复合右美托咪定对于产后自控镇痛的临床效果以及推广意义。方法选自本院2013年-2016年期间产科收治选择剖宫产分娩方式产妇826例相关临床资料作为本次分析数据来源,以对产妇使用的术后镇痛措施差异为依据将其以每组413例分为对照组与观察组,对照组泵注布托啡诺联合生理盐水,观察组患者采用布托啡诺复合右美托咪定术后静脉镇痛。对临床资料回顾性分析后归纳不同术后镇痛措施对于产妇产后镇痛效果、镇静效果、宫底高度以及安全性。结果分别在产妇剖宫产后8小时、16小时以及24小时各个时间段进行视觉模拟评分对镇痛效果做评估,从数据中可知不同时间段观察组视觉模拟评分数据均优于对照组产妇,应用统计学软件处理,P<0.05;观察组产后8小时、16小时Ramsay镇静评分数据优于对照组产妇,差异具有统计学意义,P<0.05;产后第1天、3天、5天对宫底下降高度进行测量,从数据中可知观察组产妇产后3天、5天宫底下降高度显著优于对照组产妇差异具有统计学意义,P<0.05;分别于麻醉前、麻醉后和苏醒后三个时间段接受生命指征检测,其中麻醉后和苏醒后对照组患者生命指征下降程度更为明显,对比有统计学意义,P<0.05;麻醉后观察组注射痛、恶心、呕吐、乏力等不良反应情况优于对照组,差异有统计学意义,P<0.05。结论对剖宫产分娩产妇而言,产后疼痛是影响其康复以及生活质量的重要因素,甚至部分产妇可因此出现产后抑郁,布托啡诺复合右美托咪定对剖宫产术后镇痛有着令人满意的效果,而在麻醉过程不会影响产妇的相关机体指标,利于剖宫产顺利完成,安全性高,值得推广。

Objective To understand the way of delivery cesarean section parturients by Bhutto butorphanol combined dexmedetomidine on the clinical effect of postpartum analgesia and promoting significance. Methods Selected from our hospital during 2013-2016 from cesarean delivery maternal 826 cases clinical data as the analysis of data sources, based on the difference in analgesia measures of maternal use of postoperative on the basis of the 413 cases in each group were randomly divided into control group and observation group, control group, infusion of Bhutto butorphanol combined with saline, the observation group were treated by Bhutto butorphanol combined dexmedetomidine analgesia for postoperative intravenous analgesia. Methods Retrospective analysis of clinical data for postoperative analgesia after different induction the effect of postpartum sedative effect, fundal height and safety. Results After cesarean section in 8 hours, 16 hours and 24 hours each time the visual analog scale of The analgesic effect of assessment from the data, the different time observation group visual analogue score data were better than the control group mothers, using statistical software processing, P<0.05; the observation group after 8 hours, 16 hours Ramsay sedation score data better than the control group, the difference was statistically significant, P<0.05; first days postpartum 3 days, 5 days, the decrease of uterine fundus height were measured from the data in the observation group postpartum 3 days, 5 days at the end of the falling height was significantly better than the control group were statistically significant, P<0.05; respectively before anesthesia, after anesthesia and recovery after three hours to accept life sign detection. Which after anesthesia and after waking life signs of patients in the control group decreased more significantly, there was statistically significant correlation,P<0.05; the observation group after anesthesia injection pain, nausea, vomiting, fatigue and other adverse reactions than the control group, the difference was statistically Statistical significance,P<0.05. Conclusion The cesarean delivery, postpartum pain is affecting the rehabilitation and quality of life of the important factors, and even some women may be in postpartum depression, Bhutto butorphanol combined with dexmedetomidine has a satisfactory effect on analgesia after cesarean section, in anesthesia the process does not affect the relevant indicators of maternal body, for cesarean section was successfully completed, high safety, worthy of promotion.