探析辛伐他汀联合曲美他嗪治疗、心肌梗死后心绞痛的临床疗效

Clinical Efficacy of Simvastatin Combined with Trimetazidine in the Treatment of Angina Pectoris after Myocardial Infarction

目的对辛伐他汀联合曲美他嗪治疗心肌梗死后心绞痛的临床疗效进行对比分析。方法回顾性分析孝感市孝南区书院社区卫生服务中心2014年10月-2016年10月期间收治的89例急性心肌梗死患者的临床资料,并按照数字随机法将89例患者随机分为对照组和观察组,对照组中44例患者采用常规的治疗方式进行治疗,观察组中45例患者采用常规治疗加以辛伐他汀联合曲美他嗪进行治疗,对两组的治疗效果、各项指标变化进行对比分析。结果观察组患者治疗的总有效率显著比对照组高(P<0.05),治疗后观察组血脂各项指标较治疗前疗效有显著改善(P<0.05),组间对比观察组患者改善程度高于对照组(P<0.05)。结论临床治疗急性心肌梗死后心绞痛可采用辛伐他汀联合曲美他嗪治疗,其疗效显著,能有效改善患者血脂代谢情况,提高患者生活质量,具有较高的临床应用价值。

Objective To compare the clinical efficacy of simvastatin combined with trimetazidine in the treatment of angina pectoris after myocardial infarction. Methods The clinical data of 89 patients with acute myocardial infarction admitted to the community street health service center of Xiaonan District in Xiaogan during October 2014-October 2016 were analyzed retrospectively, and randomly 89 patients were randomly divided into control group and observation group, control group 44 cases were treated with conventional treatment. In the observation group, 45 patients were treated with simvastatin and Trimetazidine, comparative analysis of the changes of the two groups of treatment effect. Results The patients in the observation group the total effective rate was significantly higher than the control group(P<0.05), blood lipid indexes of observation group after treatment than before treatment efficacy was significantly improved(P<0.05). Conclusion The clinical treatment of acute myocardial infarction angina pectoris after using simvastatin combined with trimetazidine Sibutramine treatment, it has obvious curative effect, can effectively improve blood lipid metabolism, improve the quality of life of patients, it has high value in clinical application.