老年慢性支气管炎急性发作利用盐酸氨溴索雾化吸入的临床疗效

Clinical Effect of Aerosol Inhalation of Ambroxol Hydrochloride in Elderly Patients with Acute Exacerbation of Chronic Bronchitis

目的研讨老年慢性支气管炎患者急性发作期接受盐酸氨溴索雾化吸入的临床价值。方法从本院2015年10月-2016年10月选取50例老年慢性支气管炎患者参与研究试验,并随机划分组别,Ⅰ、Ⅱ组各25例,Ⅰ组接受常规对症治疗,Ⅱ组在常规给药下接受盐酸氨溴索雾化吸入,评估该两种给药方案在临床上的应用效果,包括临床药效、平均住院日,以及喘息、咳痰/咳嗽等症状缓解时间。结果Ⅱ组在接受方案治疗后,取得了96.0%的总有效率,相比Ⅰ组的总有效率(72.0%)显著提高,数据满足P<0.05,统计学成立。Ⅱ组的喘息、咳痰/咳嗽症状缓解相比Ⅰ组均显著增快,平均住院日相比Ⅰ组显著缩短,数据满足P<0.05,统计学成立。结论采取盐酸氨溴索雾化吸入对老年慢性支气管炎患者进行急性发作期用药,方案药效理想、安全,可有效缓解相关支气管症状,值得推荐。

Objective The clinical value of ambroxol hydrochloride inhalation acute exacerbation objective study in elderly patients with chronic bronchitis. Methods In our hospital from October 2015-October 2016 50 cases of elderly patients with chronic bronchitis were randomly divided into experimental study participants, group I, II, 25 cases in each group. Group 1 received conventional symptomatic treatment, group II in routine the drug received ambroxol hydrochloride inhalation, evaluation of the two regimens in clinical application, including clinical efficacy, average hospitalization days, and wheezing, cough/expectoration symptom remission time. Results After treatment in group II, 96% achieved a total efficiency, compared to the total group efficiency(72%) was significantly increased, the data meet the P<0.05, was established. The group II wheezing, cough symptoms relieve expectoration/compared group were significantly increased, compared with group I significantly shorten the average hospitalization days, the number of According to meet P<0.05, was established. Conclusion Ambroxol hydrochloride inhalation in elderly patients with acute exacerbation of chronic bronchitis medication, drug safety, ideal scheme, can effectively alleviate the bronchial symptoms, it is recommended.