颈动脉支架植入术对脑梗死合并认知功能障碍患者认知功能的影响

Effect of Carotid Artery Stenting on Cognitive Function In Patients with Cerebral Infarction Complicated with Cognitive Impairment

目的探讨脑梗死合并认知功能障碍患者给予颈动脉支架植入术对其认知功能的影响及疗效。方法对2015年5月至2016年12月我院收治的64例认知功能障碍合并脑梗死患者,采用随机数字法将其分为对照组32例与观察组32例,对照组采用常规药物治疗,观察组给予颈动脉支架植入术,对比两组患者治疗后1月、2月、5月的认知功能变化。结果观察组患者经颈动脉支架植入术后1月、2月、5月Barthel指数明显高于对照组(P<0.05);观察组脑梗死合并认知障碍患者经治疗后MMSE评分指标显然高于对照组(P<0.05);观察组认知障碍合并脑梗死患者Mo CA评分结果明显高过对照组Mo CA评分(P<0.05)。结论采用颈动脉支架植入术治疗认知功能障碍合并脑梗死患者,可有效改善患者认知障碍,提高患者生活质量。

Objective To investigate the effect of carotid stent implantation on cognitive function in patients with cerebral infarction combined with cognitive impairment. Methods From May 2015 to December 2016, 64 patients with cognitive dysfunction complicated with cerebral infarction were treated in our hospital, were randomly divided into control group of 32 cases and observation group of 32 cases, the control group received the conventional treatment, the observation group were given carotid artery stenting, cognitive function, the cognitive function of the two groups was compared at 1 months, 2 months and 5 months after treatment. Results The observation group patients after carotid artery stenting after 1 months, 2 months, 5 months the Barthel index was significantly higher than the control group(P<0.05); patients with cerebral infarction complicated with cognitive disorder group after treatment MMSE score index was obviously higher than that of control group(P<0.05); observation group cognitive impairment combined with cerebral infarction patients Mo CA score significantly higher than the Mo CA score of control group(P<0.05). Conclusion Carotid stent implantation can effectively improve cognitive impairment and improve the quality of life in patients with cognitive dysfunction complicated with cerebral infarction.