46例梅毒阳性产妇所产新生儿梅毒血清学转归调查

46 Cases of Syphilis Positive Maternal Neonatal Syphilis Serology Outcome From the Investigation

目的了解我县2014年2月至2015年6月期间,梅毒阳性母亲所产新生儿血清学转归情况。方法取46例梅毒阳性母亲所产新生儿血清,做RPR及TPPA试验,并于第6月、第9月、第12月、第15月、第18月进行随访复查,对其血清学结果进行分析,若连续两次RPR、TPPA均为阴性,则排除先天梅毒,终止随访。结果 46例新生儿中2例在第6月复检为阴性,排除先天梅毒,第9月排除例数为16例,第12月排除例数为12例,第15月排除例数为8例,第18月排除例数为2例,确诊先天梅毒例数为4例,第6月失联例数为1例。结论产前梅毒筛查的必要性;妊娠期梅毒阳性存在高风险;梅毒阳性产妇所产新生儿梅毒血清学检查大多呈阳性,但大部分于第9个月转阴并排除先天梅毒。本文仅对我县46例梅毒感染产妇所产新生儿进行血清学分析。现将结果报告如下:

Objective To understand the positive syphilis mother neonatal serological outcomes in our county from February 2014 to June 2015.Methods 46 cases of syphilis positive mother neonatal serum, and from the RPR and TPPA test, and in June the first, the first of September, the first 12 months, the first 15 months, the first 18 months follow-up review and analyze the serological results, if two consecutive RPR and TPPA are negative, the exclusion of congenital syphilis, termination of follow-up.Results 46 newborns in 2 cases in the first 6 month review are negative, eliminate congenital syphilis, in September the first rule out the number of cases in 16 cases, the first 12 months out cases for 12 cases, eliminate the number of cases in the first 15 month for 8 cases, the first 18 months to rule out the number of cases for 2 cases, diagnosis of congenital syphilis cases for 4 cases, the first of June for 1 case of lost.Conclusion the necessity of antenatal syphilis screening;Positive for syphilis during pregnancy high-risk;Syphilis positive maternal neonatal syphilis serological examination from the most positive, but the majority of overcast and exclusion of congenital syphilis in 9 months.This article only my county of 46 cases of syphilis infection newborns from the maternal serological analysis.