探讨甲硝唑联合替硝唑对于细菌性阴道炎患者的治疗效果

To Investigate the Effect of Metronidazole Combined with Tinidazole in the Treatment of Bacterial Vaginitis

目的了解对细菌性阴道炎患者制定甲硝唑、替硝唑药物联合治疗对病情的干预和控制效果。方法分析对象来自2016-2017年于本院接受诊治细菌性阴道炎患者相关临床资料,从中选取200例,随机数字表将患者分为对照组与观察组(n=100),对应治疗方式分别为单纯甲硝唑治疗、联合替硝唑治疗。在疗程结束后对不同方案干预下患者病情治疗效果和复发情况进行比较。结果以患者病情变化为疗效判断依据,对照组与观察组判定无效例数分别为29例、8例,组间总有效率经过统计学软件处理(P<0.05),提示有意义;对患者进行平均3个月时间随访,期间观察组患者发生复发情况例数明显低于对照组,组间差异用统计学软件处理(P<0.05),提示有意义。结论对细菌性阴道炎患者在考虑治疗干预方案时,可将甲硝唑联合替硝唑作为首选治疗措施,相对于常规单一药物治疗,疗效更为突出且可有效控制治疗后复发情况,值得临床推广。

Objective To understand the intervention and control effect of metronidazole and Tinidazole combined therapy on bacterial vaginosis in patients with bacterial vaginosis. Methods to analyze the object from the 2016-2017 to accept the relevant clinical data of diagnosis and treatment of bacterial vaginitis patients in our hospital, selected from 200 cases of patients were randomly divided into control group and observation group(n=100), corresponding treatment methods were simple, combined with metronidazole for ornidazole treatment. At the end of the course, the treatment effect and recurrence of the patients under different intervention were compared. Results The patients with the basis to judge curative effect, the control group and the observation group judged invalid cases were 29 cases, 8 cases, the total effective rate after statistical treatment group(P<0.05), suggesting the significance; an average of 3 months follow-up of patients during the observation group patients occurred relapse cases significantly lower than the control group, with statistical software processing, the differences between groups(P<0.05), suggesting the significance. Conclusion For patients with bacterial vaginosis in consideration of therapeutic intervention programs, can be used as first-line treatment measures of metronidazole and Tinidazole, compared with conventional single drug treatment, the curative effect is more prominent and can effectively control the recurrence after treatment, worthy of promotion.