维持性血透患者高血压的治疗研究

Study on the Treatment of Hypertension in Maintenance Hemodialysis Patients

目的探讨不同透析方式对于维持性血透患者高血压的治疗效果。方法选择2015年1月至2017年1月来我院就诊的维持性血液透析高血压患者148例,将其随机分为对照组(n=74)和观察组(n=74),前者进行常规标准透析治疗,后者则进行可调钠透析治疗,对比两组治疗前后血压、心率和血清钠离子浓度的变化情况。结果经过3个月的治疗后,观察组血压得到了有效的控制,其舒张压和收缩压均有了明显降低,差异具有统计学意义(P<0.05),但心率和血清钠离子浓度未发生明显变化;而对照组血压水平未得到改善,心率和血清钠离子浓度也维持在治疗前的水平,差异无统计学意义(P>0.05)。结论相比于常规标准透析,可调钠透析对于患者高血压的治疗具有显著疗效,在降低患者血压的同时不对患者血清钠离子浓度和心率产生影响,是一种安全有效的治疗方法。

Objective To investigate the effect of different dialysis modalities on hypertension in maintenance hemodialysis patients.Methods From January 2015 to January 2017 in our hospital 148 cases of maintenance hemodialysis patients with hypertension,which were randomly divided into control group(n=74) and observation group(n=74),the conventional standard dialysis treatment,the latter of adjustable sodium dialysis treatment,changes of blood pressure,heart rate and serum sodium concentration before and after treatment were compared between two groups.Results After 3 months of treatment,patients in the observation group blood pressure was controlled effectively,the diastolic blood pressure and systolic blood pressure were significantly decreased,the difference was statistically significant(P<0.05),but the heart rate and serum sodium concentration did not change significantly;while the control group of patients with blood pressure level has not been improved,and heart rate the serum sodium concentration is also maintained at the level before the treatment,there was no statistically significant difference(P>0.05).Conclusion Compared to conventional standard dialysis and adjustable sodium dialysis has obvious curative effect for the treatment of patients with hypertension,the influence on reduce blood pressure of patients without serum sodium ion concentration and heart rate,is a safe and effective treatment method.