胃食管反流病患者合并幽门螺杆菌的临床诊治分析

Clinical Diagnosis and Treatment of Helicobacter Pylori in Patients with Gastroesophageal Reflux Disease

目的探讨胃食管反流病和幽门螺杆菌之间的关系。方法我院于2015年4月至2017年4月将42例胃食管反流病的患者作为研究对象进行诊治工作,并且将其随机分成对照组和观察组,每组21例。其中,对照组的患者为不进行合并治疗的患者,而观察组的患者则是需要进行合并治疗的患者。通过治疗之后,对两组患者的焦虑抑郁评分和PPI治疗效果进行比较。结果两组患者经过比较后发现,两组患者PPI经验性治疗效果、症状计分方面以及经过精神状态方面均无统计学的差异(P>0.05)。结论通过对患者进行研究后发现,合并幽门螺杆菌感染的胃食管反流病患者出现食管炎的概率进一步的降低,并且患者的食管炎对于患者的影响也进一步减少,因此幽门螺杆菌对于胃食管反流病患者的身体健康有着一定的促进作用。

Objective To investigate the relationship between gastroesophageal reflux disease(GERD) and helicobacter pylori(HP). Methods 42 patients with gastroesophageal reflux disease were treated in our hospital from April 2015 to April 2017, and were randomly divided into control group and observation group, 21 cases in each group. Among them, the patients in the control group were not treated with combination therapy, while the patients in the observation group were patients who needed to be combined treatment. After treatment, the anxiety and depression scores of the two groups were compared with those of the PPI treatment. Results After comparison, the two groups of patients with PPI experience treatment effect, symptoms score and mental status were not significant difference, two groups of patients were not significant difference(P>0.05). Conclusion After the study of the patients, we found that the incidence of gastroesophageal reflux disease patients with helicobacter pylori infection is further reduced, and the patients with esophagitis have a further reduction in the influence of the patients, so helicobacter pylori has a certain contribution to the health of the patients with gastroesophageal reflux disease.