吸入布地奈德与静脉注射甲泼尼龙治疗慢性阻塞性肺疾病急性加重期的疗效分析

Therapeutic Effect of Inhaled Budesonide and Intravenous Methylprednisolone in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease

目的对吸入布地奈德以及静脉注射甲泼尼龙治疗慢性阻塞性肺疾病急性加重期的疗效进行探讨。方法选择40例慢性阻塞性肺疾病急性加重期患者列为我院研究对象,实施吸入布地奈德治疗,为观察组。同期另外40例慢性阻塞性肺疾病急性加重期患者则实施甲泼尼龙静注治疗,为参照组。就两组患者的临床治疗情况以及预后情况展开分析和数据对比。结果两组患者治疗后的肺功能指标与治疗前相比改善显著,差异显著(P<0.05),有统计学意义;两组患者治疗后的血气指标与治疗前相比改善显著,差异显著(P<0.05),有统计学意义。结论吸入布地奈德与静注甲泼尼龙在慢性阻塞性肺疾病急性加重期的治疗效果相似,然而吸入布地奈德的不良反应较少,安全性更高。

Objective To investigate the efficacy of inhaled budesonide and intravenous injection of albinonylon in the treatment of acute exacerbation of chronic obstructive pulmonary disease. Methods Forty patients withacute exacerbation of chronic obstructive pulmonary disease were enrolled in our hospital. The inhaled budesonidewas used as the observation group. In the same period, another 40 patients with acute exacerbation of chronicobstructive pulmonary disease were treated with intraocular injection of N-wave nylon for the reference group. Theanalysis and data comparison were carried out on the clinical treatment and prognosis of the two groups of patients.Results The lung function indexes of the two groups were significantly improved compared with those beforetreatment(P<0.05). The blood gas indexes of the two groups were significantly improved compared with those beforetreatment. The difference was significant(P<0.05). Conclusion Inhaled budesonide and intravenous injection ofN-Nylon are similar in the treatment of acute exacerbation of chronic obstructive pulmonary disease. However, inhaledbudesonide has fewer adverse reactions and higher safety.