观察二甲双胍联合门冬胰岛素治疗老年糖尿病患者的临床效果

To Observe the Clinical Effect of Metformin Combined with Insulin Aspart in the Treatment of Elderly Patients with Diabetes

目的对治疗老年糖尿病患者应用二甲双胍联合门冬胰岛素的临床效果进行研究分析。方法选择老年糖尿病患者共210例作为研究分析对象,使用随机数字法,将所有患者分为观察组、对照组,对照组使用门冬胰岛素治疗,观察组在对照组治疗基础上应用二甲双胍治疗,对比两组临床效果。结果观察组患者的空腹血糖水平、餐后2h血糖水平、糖化血红蛋白水平均明显低于对照组(P<0.05);观察组患者的血糖控制达标时间明显低于对照组(P<0.05);观察组患者的血糖控制情况明显优于对照组(P<0.05),差异均有统计学意义。结论应用二甲双胍联合门冬胰岛素治疗老年糖尿病具有显著疗效,降低患者空腹血糖水平,同时未出现明显不良反应,安全性较高,值得临床推广应用。

Objective To study the clinical effect of metformin combined with insulin aspart in the treatment of elderly patients with diabetes. Methods A total of 210 elderly patients with diabetes were enrolled in the study. All patients were divided into observation group and control group by random number method. Inhaled insulin was used in the control group. Metformin was used in the observation group. Compare the clinical effects of the two groups. Results The fasting blood glucose level, postprandial blood glucose level and glycated hemoglobin level in the observation group were significantly lower than those in the control group(P<0.05). The blood glucose control compliance time of the observation group was significantly lower than that of the control group(P<0.05). The blood glucose control of the observation group was significantly better than that of the control group(P< 0.05), and the difference was statistically significant. Conclusion The use of metformin combined with insulin aspart in the treatment of senile diabetes has a significant effect, reducing the level of fasting blood sugar in patients, at the same time, there were no obvious adverse reactions, and the safety was high, which was worthy of clinical application.