黄体酮治疗黄体功能不全所致先兆流产的临床观察

Clinical Observation of Progesterone in the Treatment of Threatened Abortion Caused By Luteal Insufficiency

目的探索黄体酮对孕妇黄体功能不全造成先兆流产的临床治疗效果。方法我们将在2016年8月至2017年8月的黄体功能不全所致的72类先兆流产患者作为研究对象,根据患者的意愿划分为各36例的两组,进行分析、比较。对照组主要是接受了肌内黄体酮针剂的注射,实验组则以黄体酮胶囊口服的方式。结果对照组目前的总有效率是91.67%;相对于实验组能看到的总有效率为4.44%。从不良反应的发生上看,多存在肠道不适、乳房胀痛的情况,但两组患者的差异不大,分别为11.1%和13.9%。结论黄体酮功能不全时极易造成患者先兆流产,对此我们采取的黄体酮针剂肌内注射和更方便的口服黄体酮胶囊进行比较,采取口服胶囊的方式是略微优于肌内注射的方式,对临床实验具有很大价值,不仅安全可靠,而且效果明显有效。

Objective To explore the clinical therapeutic effect of progesterone on threatened abortion caused by luteal insufficiency in pregnant women. Methods We conducted 72 types of threatened abortion patients with luteal dysfunction from August 2016 to August 2017. The patients were divided into 36 groups according to the patient’s wishes, and analyzed and compared. The control group received mainly intramuscular progesterone injections, while the experimental group received oral progesterone capsules. Results The total effective rate of the control group was 91.67%;the total effective rate was 4.44% compared with the experimental group. From the occurrence of adverse reactions, there were many cases of intestinal discomfort and breast pain, but the difference between the two groups was not significant, 11.1% and 13.9%, respectively. Conclusion The progesterone dysfunction is very likely to cause threatened abortion. For the intramuscular injection of progesterone injection and the more convenient oral progesterone capsule, the method of taking oral capsule is slightly better than intramuscular injection. It is of great value to clinical trials, not only safe and reliable, but also effective and effective.