阿司匹林在血栓性脑梗死急诊治疗中的临床效果评价

Clinical Effect Evaluation of Aspirin in Emergency Treatment of Thrombotic Cerebral Infarction

目的探讨阿司匹林在血栓性脑梗死急诊治疗中的临床效果。方法收集2017年8月至2018年8月入院的100例血栓性脑梗死急诊患者随机分为两组,对照组患者给予传统常规治疗,观察组患者则加用阿司匹林,比较两组患者神经缺损、日常生活能力指标、总有效率、凝血指标与不良反应。结果观察组患者治疗后14d的NIHSS评分(6.42±1.01)、PT(8.01±0.76)、APTT(15.42±5.33)、Fib(2.84±0.60)与D-二聚体水平(0.50±0.13)组间比较显著性低于对照组(8.17±1.23,10.01±0.82,21.37±5.81,3.38±0.75,0.89±0.20),BI指数(75.12±8.08)显著性高于对照组(68.49±7.86);总有效率(90%)明显高于对照组(74%),差异具有统计学意义(P<0.05);两组患者不良反应率不存在明显差异(P>0.05)。结论阿司匹林在血栓性脑梗死急诊治疗中的临床效果显著,具有借鉴意义。

Objective to investigate clinical effect of aspirin in emergency treatment of thrombotic cerebral infarction. Methods collect 100 cases emergency patients with thrombotic cerebral infarction treated in our hospital from August 2017 to August 2018, divide them into two groups randomLy, control group was treated with routine treatment, and observation group with aspirin based on control group. Compare neurological deficits, daily living ability index, total effective rate, coagulation index and adverse reactions between two groups. Results 14 d after treatment in observation group, NIHSS scores were(6.42±1.01), PT(8.01±0.76), APTT(15.42±5.33), Fib(2.84±0.60) and D-dimer level(0.50±0.13), significantly lower than control group(8.17±1.23, 10.01±0.82, 21.37±5.81, 3.38±0.75, 0.89±0.20), BI index(75.12±8.08) was significantly higher than control group(68.86±0.13). Total effective rate(90%) was significantly higher than control group(74%), difference showed statistical significance(P<0.05);adverse reaction rate showed no significant difference between two groups(P>0.05). Conclusion Aspirin has significant clinical effect in emergency treatment of thrombotic cerebral infarction, with reference significance.