观察阿托伐他汀联合依折麦布治疗高血脂症的有效性和其安全性

To Observe the Efficacy and Safety of Atorvastatin combined with Ezetimibe in the Treatment of Hyperlipidemia

目的探究高脂血症应用阿托伐他汀联合依折麦布治疗的临床效果。方法此次实验对象全部选自2017年3月至2018年11月期间在本院治疗的56例高脂血症患者,分成两组,即研究组(n=29)和对照组(n=27),两组患者全部使用阿托伐他汀治疗,在此基础上研究组联合依折麦布治疗,将两种治疗效果分析对比。结果研究组和对照组在治疗后的TC、TG、LP-a、LDL-C和HDL-C水平以及总有效率差异上,均有统计学意义(P<0.05);两组在不良反应发生率差异上,无统计学意义(P>0.05)。结论高脂血症应用阿托伐他汀联合依折麦布治疗的临床效果较好,不仅能够有效控制患者血脂水平,且安全性较高。

Objective To evaluate the clinical efficacy and safety of dexamethasone combined with atorvastatin in the treatment of hyperlipidemia. Methods All the subjects in this study were selected from 56 patients with hyperlipidemia who were treated in our hospital from March 2017 to November 2018. They were divided into two groups, the study group(n=29) and the control group(n=27), both groups were treated with atorvastatin, and the study group was treated with ezetimibe to compare the effects of the two treatments. Results The levels of apo-B,TG, TC, LDL-C and HDL-C in the study group and the control group were statistically significant(P< 0.05). In the total effective rate of treatment, the study group(90.91%) was more than the control group(61.90%), the difference between the groups was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05). Conclusion The difference of TC, TG, LP-a, LDL-C, HDL-C levels and total effective rate between the study group and the control group were statistically significant(P<0.05);the incidence of adverse reactions in the two groups. There was no statistically significant difference(P>0.05).