新生儿肺炎患者使用盐酸氨溴索和布地奈德雾化吸入治疗的疗效探究

Therapeutic Effect of Nebulized Inhalation of Ambroxol Hydrochloride and Budesonide in Neonates with Pneumonia

目的分析采用盐酸氨溴索和布地奈德雾化吸入治疗对新生儿肺炎的治疗效果。方法纳入我院在2017年6月至2018年6月收治的764例新生儿肺炎,将患儿采用随机数字表法均分为对照组(n=382)和观察组(n=382),分别予以盐酸氨溴索治疗和盐酸氨溴索、布地奈德雾化吸入治疗。将2组患儿的治疗效果进行对比分析。结果观察组治疗总有效率95.55%高于对照组85.34%,P<0.05。观察组不良反应发生率为3.93%低于对照组的12.04%,P<0.05。观察组咳嗽消失时间、呼吸困难消失时间、湿罗音消失时间、住院用时均短于对照组,P<0.05。结论采用盐酸氨溴索和布地奈德雾化吸入治疗对新生儿肺炎的治疗效果显著,可以促进患儿快速康复。

Objective To analyze the therapeutic effect of ambroxol hydrochloride and budesonide inhalation on neonatal pneumonia. Methods A total of 764 neonatal pneumonia patients admitted to our hospital from June 2017 to June 2018 were enrolled. The children were divided into the control group(n=382) and the observation group(n=382)by random number table method. They were treated with ambroxol hydrochloride and ambroxol hydrochloride and budesonide. The therapeutic effects of the two groups of children were compared and analyzed. Results The total effective rate of the observation group was 95.55% higher than that of the control group(85.34%, P<0.05). The incidence of adverse reactions in the observation group was 3.93% lower than that in the control group(12.04%, P<0.05). The disappearance time of cough, the time of disappearance of dyspnea, the disappearance time of wet rales, and the time of hospitalization were shorter in the observation group than in the control group, P<0.05. Conclusion The therapeutic effect of ambroxol hydrochloride and budesonide inhalation on neonatal pneumonia is significant, which can promote the rapid recovery of children.