联合检测血清同型半胱氨酸及幽门杆菌感染在急性脑梗死诊治中的价值分析

Value of Combined Detection of Serum Homocysteine and Helicobacter Pylori Infection in the Diagnosis and Treatment of Acute Cerebral Infarction

目的研讨急性脑梗死患者接受血清同型半胱氨酸(Hcy)以及幽门螺杆菌(Hp)感染联合检测的临床意义。方法从我院2016年5月至2018年10月收治的急性脑梗死患者中抽选120例作为实验对象,并纳入脑梗死组,同期选择120例健康体检人员作为健康组,对两组的血清Hcy水平及Hp感染情况进行检测并比较。结果脑梗死组的血清Hcy值为(23.31±3.19)μmol/L,Hp感染率为86.7%(104/120),对比健康组的血清Hcy值(13.28±2.51)μmol/L与Hp感染率29.2%(35/120)均明显提升,有统计学意义(P<0.05)。且与脑梗死非Hp感染组对比,脑梗死Hp感染组的血清Hcy值以及各项血脂指标值均发生明显变化,比较有统计学意义(P<0.05)。结论联合检测急性脑梗死患者的血清Hcy水平与Hp感染情况,对及时确诊患者病情、预估病情程度有明显的帮助,值得推荐。

Objective To investigate the clinical significance of combined detection of serum homocysteine(Hcy) and Helicobacter pylori(Hp) infection in patients with acute cerebral infarction. Methods A total of 120 patients with acute cerebral infarction admitted to our hospital from May 2016 to October 2018 were enrolled in the cerebral infarction group. One hundred and twenty healthy medical examiners were selected as the healthy group for the two groups. Serum Hcy levels and Hp infection were detected and compared. Results The serum Hcy value of the cerebral infarction group was(23.31±3.19) μmol/L, and the Hp infection rate was 86.7%(104/120). Compared with the healthy group, the serum Hcy value(13.28±2.51) μmol/L and Hp infection rate. 29.2%(35/120) were significantly improved,which was statistically significant(P<0.05). Compared with the non-Hp infection group with cerebral infarction, the serum Hcy value and the blood lipid index of the Hp infection group were significantly different(P<0.05). Conclusion Combined detection of serum Hcy level and Hp infection in patients with acute cerebral infarction is helpful for timely diagnosis of patients’ condition and estimation of disease severity. It is recommended.