我院血培养常见病原菌及药敏研究

Study on Common Pathogens and Drug Susceptibility of Blood Culture in Our Hospital

目的研究分析血培养常见病原菌及其药敏试验。方法选取2850份血培养标本,观察分析其所分离到的常见病原菌与药敏试验结果。结果 (1)所有样本血培养阳性率与菌株分布情况:在送检的17100份血培养标本中,分离出病原菌1625株,阳性率为9.5%;其中革兰阴性菌848(52.2%)株、革兰阳性菌710(43.7%)株、真菌67(4.1%)株;(2)药敏试验分析:铜绿假单胞菌对头孢他啶、庆大霉素与亚胺培南耐药率最低;鲍曼不动杆菌对替卡西林、亚胺培南耐药率最低;阴沟肠杆菌对亚胺培南、复方新诺明、替卡西林等耐药率最低。在革兰氏阳性杆菌中,均对万古霉素耐药率最低。结论在我院血培养中其病原菌分布较为复杂,经联合药敏试验则可为临床抗生素的应用提供可靠依据,以减少耐药菌出现,降低二重感染率。

Objective To study the common pathogens in blood culture and their drug susceptibility tests.Methods Two thousand eight hundred and fifty blood culture specimens were selected to observe the common pathogens and drug susceptibility test results.Results(1)The positive rate of blood culture and the distribution of strains in all samples:1625 strains of pathogenic bacteria were isolated from 17100 blood culture specimens,the positive rate was 9.5%;Gram-negative bacilli 848(52.2%)Strain,Gram-positive bacillus 710(43.7%)strain,fungus67(4.1%)strain;(2)Susceptibility test analysis:Pseudomonas aeruginosa resistance to ceftazidime,gentamicin and imipenem The lowest;Acinetobacter baumannii had the lowest resistance rate to ticarcillin and imipenem;Enterobacter cloacae had the lowest resistance rate to imipenem,cotrimoxazole and ticarcillin.In Gram-positive bacilli,the resistance rate to vancomycin was the lowest.Conclusion The distribution of pathogens in blood culture in our hospital is more complicated,and the combined drug sensitivity test can provide a reliable basis for the application of clinical antibiotics.To reduce the emergence of drug-resistant bacteria and reduce the rate of double infection.