硫酸镁+硝苯地平治疗对妊高症患者妊娠结局的影响研究

A Study on Effects of Treating Pregnancy Induced Hypertension with Magnesium Sulfate + Nifedipine on Pregnancy Outcomes of Patients

目的探讨硫酸镁+硝苯地平治疗对妊高症患者妊娠结局的影响研究。方法选取我院2016年5月至2018年1月68例妊高症患者,根据随机数表法分为观察组(硫酸镁+硝苯地平治疗)与对照组(硫酸镁治疗),每组各34例,对比妊娠结局、治疗效果。结果治疗后观察组平均动脉压、24h蛋白尿比较均低于对照组(P<0.05);观察组治疗有效率显著高于对照组(P<0.05);观察组剖宫产、早产、胎膜早破均低于对照组(P<0.05)。结论硫酸镁+硝苯地平治疗对妊高症患者妊娠结局的影响显著,值得推广。

Objective To explore the effects of treating pregnancy-induced hypertension with magnesium sulfate+nifedipine on pregnancy outcomes of patients.Methods 68 patients with pregnancy-induced hypertension who were treated in our hospital from May 2016 to January 2018 were selected.They were divided into the observation group(treated with magnesium sulfate combined with nifedipine)and the control group(treated with magnesium sulfate)according to the random number table method,with 34 patients in each group.Then pregnancy outcomes and efficacy were compared.Results Firstly,the mean arterial pressure and 24 h proteinuria of the observation group were both lower than those of the control group after treatment(P<0.05).Secondly,the effective rate of the observation group was significantly higher than that in the control group(P<0.05).Thirdly,the rates of cesarean section,premature delivery and premature rupture of membrane of the observation group are all lower than those of the control group(P<0.05).Conclusion The application of magnesium sulfate+nifedipine in the treatment of pregnancy-induced hypertension has significant benefit to pregnancy outcomes of patients and therefore is worthy of promotion.