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丹霞铁皮石斛的降血糖实验研究 被引量:6

Experimental Study on Hypoglycemic Effect of Dendrobium Candidum
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摘要 目的观察丹霞铁皮石斛对四氧嘧啶所致高血糖大鼠的降血糖作用。方法采用水煮法提取丹霞铁皮石斛提取物。建立四氧嘧啶糖尿病大鼠模型,实验分模型组、二甲双胍对照组、广西石斛组、丹霞石斛组。灌胃给药,每5 d测定各组大鼠的空腹血糖水平。结果注射四氧嘧啶3d后,大鼠血糖明显增高(P<0.01);与模型组比,不同时间各治疗组大鼠血糖显著降低(P<0.05),丹霞石斛与广西石斛无明显差异。结论丹霞铁皮石斛能显著降低四氧嘧啶糖尿病大鼠血糖。 Objective To observe the hypoglycemic effect of Dendrobium candidum on alloxan-induced hyperglycemia rats.Methods The extract of Dendrobium officinale was extracted by boiling method.A rat model of alloxan diabetes mellitus was established,which was divided into model group,metformin control group,Guangxi Dendrobium group and Dendrobium nephensi group.Gavage administration,the fasting blood glucose level of each group of rats was measured every 5 days.Results 3 days after injection of alloxan,the blood glucose of rats increased significantly(P<0.01),compared with the model group,the blood glucose of rats in each treatment group decreased significantly(P<0.05)at different times,and there was no significant difference between Dendrobium nephensi and Dendrobium in Guangxi.Conclusion The Dendrobium candidum can significantly reduce the blood glucose in rats with tetraoxypyrimidine diabetes mellitus.
作者 胡宗礼 何文倩 王青华 吴彩云 吴晓敏 黄美玉 白音 HU Zong-li;HE Wen-qian;WANG Qing-hua;WU Cai-yun;WU Xiao-min;HUANG Mei-yu;BAI Yin(Yingdong Life Science School of Shaoguan College,Shaoguan,Guangdong 512005)
出处 《智慧健康》 2019年第23期40-41,52,共3页 Smart Healthcare
基金 广东省基础研究与应用研究重大项目(2016KZDXM010)
关键词 丹霞铁皮石斛 四氧嘧啶 血糖 大鼠 Dendrobium candidum Alloxan Blood glucose Rat
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