探讨不同止吐药预防全麻术后舒芬太尼静脉自控镇痛恶心呕吐的疗效

Curative Effect Exploration of Different Antiemetic Drugs in Preventing Nausea and Vomiting after General Anesthesia with Sufentanil Intravenous Controlled Analgesia

目的探讨不同止吐药预防全麻术后舒芬太尼静脉自控镇痛恶心呕吐的疗效。方法纳入2017年9月至2018年9月我院的90例全麻手术患者,随机方法分成3组各30例,在术后舒芬太尼静脉自控镇痛中,A组术毕加入盐酸托烷司琼5mg,B组术毕加入氟哌利多5mg,C组术毕加入生理盐水稀释至110mL,对比应用效果。结果 A、B两组的治疗优良率均明显高于C组,A组的不良反应发生率明显低于B组(P<0.05)。三组术后不同时间点的BCS评分对比差异无显著性(P>0.05)。结论盐酸托烷司琼应用于预防全麻术后舒芬太尼静脉自控镇痛恶心、呕吐安全有效。

Objective To investigate curative effect of different antiemetic drugs in preventing nausea and vomiting after general anesthesia with sufentanil intravenous controlled analgesia.Methods Choose 90 cases general anesthesia patients in our hospital from September 2017 to September 2018,divide them into three groups randomly:30 cases in each group.During patient-controlled sufentanil intravenous analgesia after operation,group A was treated with 5 mg tropisetron hydrochloride at the end of operation,group B with 5 mg droperidol,and group C with 110 ml saline.Compare application effect.Results Excellent and good rates of treatment in group A and B were significantly higher than group C,and incidence of adverse reactions in group A was significantly lower than group B(P<0.05).BCS scores showed no significant difference between three groups at different time points after operation(P>0.05).Conclusion Tropisetron hydrochloride is safe and effective in preventing nausea and vomiting after general anesthesia with sufentanil intravenous controlled analgesia.