2型糖尿病采用阿卡波糖的整体临床效果分析

Overall Clinical Effect Analysis of Acarbose on Type 2 Diabetes Mellitus

目的分析2型糖尿病采用阿卡波糖的整体临床效果。方法对照组采用科学饮食运动控制,并口服二甲双胍进行口服降糖治疗,研究组在对照组全部方案基础上加用阿卡波糖口服降糖治疗。对比两组疗效,治疗前后的空腹血糖(FBG)、餐后2h血糖(2hPG)、糖化血红蛋白(HbA1c)水平,统计两组不良反应。结果研究组总有效率90.38%,显著高于对照组73.08%(P<0.05)。两组治疗前FBG、2hPG及HbA1c对比无显著差异(P>0.05);两组治疗后上述指标均比治疗前显著好转,研究组治疗后上述指标均显著好于同期的对照组(P<0.05)。两组均无显著不良反应发生。结论 2型糖尿病采用阿卡波糖的临床疗效确切,可显著改善血糖水平,安全性好。

Objective To analyze overall clinical effect of acarbose on type 2 diabetes mellitus.Methods Control group was treated with scientific diet and exercise control,oral metformin for oral hypoglycemic treatment.Research group was treated with oral acarbose on the basis of all schemes of control group.Compare curative effects of two groups,levels of fasting blood glucose(FBG),postprandial blood glucose(2 hPG)and glycosylated hemoglobin(HbA1 c)before and after treatment,carry on statistical analysis of adverse reactions of two groups.Results Total effective rate was 90.38%in research group,which was significantly higher than 73.08%in control group(P<0.05).Difference showed no significant in FBG,2 hPG and HbA1 c between two groups before treatment(P>0.05);after treatment,above indexes in both groups were significantly better than before treatment,and above indexes in research group were significantly better than control group after treatment(P<0.05).There were no significant adverse reactions in both groups.Conclusion Acarbose has accurate effect on type 2 diabetes mellitus,which can improve blood sugar level significantly with good safety.