舒芬太尼复合依托咪酯在ERCP的应用

Application of Sufentanil Combined with Etomidate in ERCP

目的探讨分析舒芬太尼复合依托咪酯在经内镜逆行性胰胆管造影(ERCP)的应用效果。方法选取我院于2018年1月至2019年1月收治的106例行ERCP患者作为本次研究对象,采用随机数表的方式分为观察组与对照组,两组53例;给予对照组患者应用舒芬太尼复合丙泊酚缓慢静推;给予观察组患者应用舒芬太尼复合依托咪酯缓慢静推。观察对比两组患者在术前(T1)、术中(T2)、术毕(T3)的血氧饱和度(SpO2)、心率(HR)以及平均动脉压(MAP)指标以及两组患者的手术时间和清醒时间。结果两组患者术前以及术后血氧饱和度(SpO2)、心率(HR)以及平均动脉压(MAP)对比差异无统计学意义(P>0.05);观察组患者术中心率(HR)以及平均动脉压(MAP)均显著高于对照组,差异具有统计学意义(P<0.05);两组患者手术时间以及麻醉清醒时间对比差异无统计学意义(P>0.05)。结论应用舒芬太尼复合依托咪酯在ERCP的术中对患者心率以及平均动脉压的影响较少,具有临床应用推广价值。

Objective To investigate the effect of sufentanil combined with etomidate on endoscopic retrograde cholangiopancreatography(ERCP).Methods A total of 106 patients with ERCP who were admitted to our hospital from January 2018 to January 2019 were enrolled in this study.They were randomly divided into observation group and control group,and 53 patients in each group.The patients in the group were treated with sufentanil and propofol slowly.The patients in the observation group were given a slow static push with sufentanil and etomidate.The blood oxygen saturation(SpO2),heart rate(HR)and mean arterial pressure(MAP)before operation(T1),during operation(T2),after operation(T3)were observed and compared between the two groups.Results There were no significant differences in preoperative and postoperative blood oxygen saturation(SpO2),heart rate(HR),and mean arterial pressure(MAP)between the two groups(P>0.05).The heart rate(HR)and mean arterial pressure(MAP)in the observation group were significantly higher than those in the control group during the operation(P<0.05).There was no significant difference in the operation time and anesthesia time between the two groups(P>0.05).Conclusion The application of sufentanil combined with etomidate has little effect on the heart rate and mean arterial pressure of patients with ERCP,and it has clinical application value.