2009～2015年湖南省肿瘤登记地区口腔癌发病与死亡分析

Incidence and Mortality of Oral Cancer in Registry Regions of Hunan Province,2009～2015

[目的]分析2009~2015年湖南省肿瘤登记地区口腔癌发病与死亡情况。[方法]收集2009~2015年湖南省24个肿瘤登记点口腔癌新发病例、死亡病例,计算口腔癌的发病率、死亡率、0~74岁累积率、35~64岁截缩率等指标,标化率采用2000年全国人口普查标准人口构成和Segi’s标准人口构成作为标准。[结果] 2009~2015年湖南省24个肿瘤登记地区共收集新发口腔癌病例1712例,口腔癌死亡病例723例。所有口腔癌病例病理组织学诊断比例98.66%,只有死亡医学证明书比例0.99%,死亡/发病比为0.42。全省口腔癌发病率4.22/10万,中标发病率为3.14/10万,世标发病率3.00/10万,0~74岁累积率为0.33%,截缩发病率为6.71/10万。城市地区居民口腔癌的发病率是6.15/10万,中标发病率为4.44/10万,农村地区居民口腔癌的发病率3.16/10万,中标发病率为2.40/10万,城市居民口腔癌发病高于农村。男性口腔癌发病率6.43/10万,中标发病率为4.80/10万,女性口腔癌发病率为1.87/10万,中标发病率为1.41/10万,男性口腔癌发病率高于女性,口腔癌发病顺位男性居全部恶性肿瘤第9位,女性居第18位。全省居民口腔癌死亡率为2.10/10万,中标死亡率为1.24/10万,世标死亡率1.20/10万,0~74岁累积率为0.14%,截缩死亡率为2.44/10万。城市地区居民口腔癌死亡率是2.74/10万,中标死亡率是1.90/10万,农村地区居民口腔癌死亡率是1.75/10万,中标死亡率是1.01/10万,城市居民口腔癌死亡率比农村居民高。男性口腔癌死亡率是2.87/10万,中标死亡率是2.05/10万,女性口腔癌死亡率是1.28/10万,中标死亡率是0.41/10万,男性高于女性,口腔癌死亡顺位男性居全部恶性肿瘤的第11位,女性居第20位。[结论]口腔癌是威胁湖南省男性特别是城市男性居民身心健康的恶性肿瘤之一。湖南省是槟榔消费大省,积极对全民进行槟榔有害口腔健康的宣传教育,以及加强控烟等预防工作,应作为湖南省口腔癌防控的重点。

[Purpose]To analyze the oral cancer incidence and mortality in the registry regions of Hunan province in 2009~2015.[Methods]New cases and death cases of oral cancer in 24 cancer registration areas of Hunan in 2009~2015 were collected.Descriptive analysis included incidence/mortality stratified by area,gender,and age group.Cumulative incidence/mortality rates(0~74 years)and truncation rate(35 and 64 years)were calculated.The Chinese population census in2000 and Segi’s world population were used for calculating the age-standardized cancer incidence/mortality rates.[Results]The total new oral cancer cases and oral cancer deaths were 1712 and 723 in 24 cancer registries in Hunan province in 2009~2015.The morphology verified cases(MV%)accounted for 98.66%and 0.99%of incident cases were identified through death certifications only(DCO%)with mortality to incidence ratio of 0.42.The crude incidence of oral cancer in Hunan province was 4.22/10~5,the age-standardized incidence rates by Chinese standard population(ASIR China)and by world standard population(ASIR world)were 3.14/10~5 and 3.00/10~5 with the cumulative incidence rate(0~74 years)of 0.33%,the truncation incidence was 6.71/10~5.The oral cancer incidence in urban areas was 6.15/10~5,and the ASIR China was 4.44/10~5.The oral cancer incidence in rural areas was 3.16/10~5,and the ASIR China was 2.40/10~5.The oral cancer incidence was higher in urban areas than that in rural areas.The oral cancer incidence in males was 6.43/10~5,and the ASIR China was 4.80/10~5.The oral cancer incidence in females was 1.87/10~5,and the ASIR China was 1.41/10~5.The oral cancer incidence was higher in males than that in females.Incidence of oral cancer ranked the 9th among males and the 18th among females in all cancers.The oral cancer mortality in Hunan cancer registries in 2009~2015 was 2.10/10~5,the age-standardized mortality rates by Chinese standard population(ASMR China)and by world standard population(ASMR world)were 1.24/10~5 and 1.20/10~5,respectively,and the cumulative mortality rate(0~74 years)was 0.14%,the truncation mortality were 2.44/10~5.The oral cancer mortality in urban areas was 2.74/10~5,and the ASMR China was 1.90/10~5.The oral cancer mortality in rural areas was 1.75/10~5,and the ASMR China was 1.01/10~5.The oral cancer mortality was higher in urban areas than that in rural areas.The oral cancer mortality in males was 2.87/10~5,and the ASMR China was 2.05/10~5.The oral cancer mortality in females was 1.28/10~5,and the ASMR China was 0.41/10~5.The oral cancer mortality was higher in males than that in females.Mortality of oral cancer ranked the 11th among males and the 20th among females in all cancers.[Conclusion]Oral cancer is one of the malignant tumors threatening the health of Hunan residents,especially for men who live in urban areas.For prevention and control of oral cancer,health education of quiting betel nut chewing and smoking needs to be strengthened in Hunan province.