摘要
硝苯啶对光不稳定。在漫射光和钨灯光下其甲醇溶液的光解为表观一级反应,并受各种因素影响。本文报道波长、受光强度和浓度对光解的影响。在漫射光下表观速度常数为灯光下的1.6倍,而初始浓度降低可使反应速度常数扩大。
Nifedipine is a photosensitive compound and subjected to degrada-tion in apparent first order reaction for its methanolic solution.The reaction rateconstant under diffused light is 1.6 times those under tungsten lamp.As for theinfluence of the initial concentration on reaction rate,kapp.5.28mg/100ml=13.28×10^(-3)min^(-1);kapp.42.60mg/100ml=3.81×10^(-3)min^(-1).
出处
《医药工业》
CAS
1987年第7期313-315,共3页
关键词
硝苯啶
光降解反应
表观一级反应
nifedipine
photochemical degradation
apparent first order reaction
