负性情绪影响创面愈合的研究现况及进展

Current status and progress of study on the effect of negative emotions on wound healing

创伤、烧伤不仅导致创面的产生,还作为应激源对患者造成心理上的影响,使之产生焦虑、抑郁等负性情绪。目前针对这类应激导致负性情绪的机制研究已较明确,这些负性情绪既与创面有关,也与患者自身性格密切相关。但负性情绪是否对创面愈合有影响、如何影响,尚未有明确或统一的意见。本文分别从炎症递质、免疫、神经内分泌系统三方面分析负性情绪对创面愈合的影响。

Trauma,burns,etc.,not only lead to the production of the wound,but also cause psychological impacts on patients as a source of stress. At present,the research on the mechanism of the negative emotion caused by these stress has been more explicit. These negative emotions are not only related to the wound,but also closely related to the patient' s own personality,but whether negative emotion has influence on wound healing and how to influence,are not yet clear or have not yet a uniform opinion. In this paper,the effects of negative emotion on wound healing are analyzed from three aspects of the inflammatory mediators,immune system and neuroendocrine system.