一种可提供循环可控的动态力学刺激的组织工程动态培养仪

A tissue engineering dynamic culture instrument to provide cyclic dynamic mechanical stimulation

为工程组织提供力学刺激,以提高培养效果的组织工程动态培养越来越受到关注。研究表明,周期性变化的力学刺激相比持续恒定的力学刺激更能模拟人体生理环境,因而更有利于工程组织的生长和分化。但现有的组织工程动态培养仪或生物反应器多采用恒定的力学刺激为工程组织提供培养环境。为了利用周期性变化的力学刺激改善培养效果,笔者研发了此组织工程动态培养仪。该培养仪通过单片机控制系统实现其核心功能,提供可以调节的周期性的力学刺激。

The dynamic training of tissue engineering,which improves the training effect by providing mechanical stimulation for the engineering tissue,are getting more and more attention.Studies have shown that mechanical stimulation of cyclical changes simulate the physiological environment of human body more than continuous mechanical stimulation,which is more advantageous to the growth and differentiation of engineering tissues.However,the existing tissue engineering dynamic culture instrument or bioreactor usually uses constant mechanical stimulation to provide training environment for the engineering tissues.In order to improve the training effect by using the cyclic mechanical stimulation,the authors developed this tissue engineering culture instrument.The cultivation instrument achieves its core functions through a single-chip control system and provides an adjustable periodic mechanical stimulation.