右心声学造影发泡试验在诊断卵圆孔未闭中的临床价值

The clinical value of foaming experiment of right heart contrast echocardiography on the diagnosis of patent foramen ovale

目的探讨右心声学造影发泡试验在诊断卵圆孔未闭(PFO)中的临床应用价值。方法回顾性分析于我院就诊的90例急性缺血性脑卒中患者(观察组)和90例非卒中患者(对照组)的临床资料。结果两组TTE静息RLS与TTE静息LRS检出率无显著性差异(P>0.05);而观察组PFO与PFO合并ASA的检出率均明显高于对照组,差异均具有统计学意义(P<0.05)。右心声学造影对观察组卵圆孔未闭的敏感性、特异性、阳性预测值、阴性预测值、准确性均高于经颅多普勒发泡试验(P<0.05)。结论右心声学造影发泡试验诊断卵圆孔未闭具有确切的临床应用价值。

Objective To explore the clinical application value of foaming experiment of right heart contrast echocardio-graphy on the diagnosis of patent foramen ovale. Methods The clinical data of 90 patients with acute ischemic stroke (obser-vation group) and 90 non stroke patients (control group) who were treated in our hospital were retrospectively analyzed. Re-sults TTE resting RLS and TTE resting LRS detection rates in two groups had no significant difference (P>0.05), while in the observation group, PFO and PFO combined with ASA detection rate was significantly higher than control group with statistical significance (P<0.05). Right heart contrast echocardiography had higher sensitivity, specificity, positive predictive value, nega-tive predictive value, accuracy than foaming experiment of transcranial doppler ultrasound on the diagnosis of patent foramen o-vale. Conclusion Foaming experiment of right heart contrast echocardiography has certain clinical application value on the diagnosis of patent foramen ovale.