中国少数民族乙二醛酶I的遗传多态性

GENETIC POLYMORPHISM OF GLYOXALASE I IN NATIONAL MINORITIES OF CHINA

用琼脂糖平板电泳技术研究了中国11个少数民族的GLO I基因的遗传多态性,这些民族的GLO^1频率分布范围为0.2466～0.1050,以11个民族总计2910个样本计算的GLO^1频率为0.1584。GLO I基因在中国少数民族中的频率分布存在显著性差异,在中国的地理分布与其在世界的分布存在一定联系。

The polymorphism of GLO I gene was investigated by agarose gel electrophorises in ele ven ethnic groups of China. The testeis were sampled from the following nationalities: Yi 209 from Butuo county. Sichuan province; Tibetan 198 from Lhasa city, Tibet Autono mous Region; Man 205 from Xiuyan Man Autonomous County, Liaoning province; Yao 209 from Yao Autonomous County, Guangxi Zhuang Autonomous Region; Hani 219 from Yuanjiang Hani Yi Dai Autonomous County, Yunnan province; Uygur 219 from Urumqi City, Xingjiang Uygur Autonomous Region, Hui 219 from Tongxin County, Ningxia Hui Auto nomous Region; Dong 201 from Sanjiang Dong Autonomous County, Guangxi Zhuang Au tonomous Rigion; Bai 203 from Jianchuan County, Yunnan province; Tujia 200 and Miao 200 from Jishou City, Hunan qrovince. Values of GLO^1 frequency for each population were as follows: Yi 0.1244, Tibetan 0.1338, Man 0.1317, Yao 0.1196, Hani 0.1507, Uygur 0.2466, Hui 0.1621, Dong 0.1866, Bai 0.1921, Tujia 0.1507, and Miao 0.1600. A significant difference of distribution of GLO I gene frequencies was found between ethnic groups of China. And geographic distribution of GLO I gene in Chinese populations was related to that in the world.