摘要
作者采用G、C显带及Ag-NOR技术,对人肝癌细胞株SMMC-7721作细胞遗传学研究。该细胞株染色体众数为58。在所有细胞中均发现多结构异常的染色体,对其中出现频率较高的标记染色体,作了简要描述,并与国内外已发表的人肝癌细胞染色体进行了比较。结果提示,某些类似的特异标记染色体,可能与肝癌的发生、发展有关。
Cytogenetic studies were performed on human hepatoma cell line (SMMC-7721) using G. C banding and silver stained nucleolar organizer regions (Ag-NOR) techniques. SMMC-7721 was a hyperdiploid with modal number of 58 chromosomes. Abnormal chromosomes of multiple structure were found in all cells. The structure of marker chromosome with high frequency was simply described.
出处
《中华医学遗传学杂志》
CAS
1987年第2期81-83,131,共4页
Chinese Journal of Medical Genetics
