超声内镜引导细针穿刺对胰腺癌的诊断价值

Diagnostic value of endoscopic ultrasound guided fine needle aspiration in patients with pancreatic carcinoma

目的探讨胰腺癌临床特点及超声内镜引导细针穿刺(EUS-FNA)对胰腺癌的诊断价值。方法对2011年9月至2013年3月安徽医科大学附属安徽省立医院收治的68例经手术病理证实的胰腺癌患者的临床特点、EUS-FNA病理学结果进行分析。结果 68例患者包括男性47例,女性21例,年龄42~82岁。肿瘤最大直径11~42 mm。21例(31%,21/68)位于胰头部,12例(18%,12/68)位于胰颈部,17例(25%,17/68)位于胰体部,18例(26%,18/68)位于胰尾部。EUS-FNA诊断胰腺癌的敏感度为88%,特异度为100%,阳性预测值为100%。穿刺组织病理学阳性率为84%(57/68),而穿刺细胞保存液细胞学阳性率为38%(26/68)。无一例出现急性胰腺炎、胰周感染、腹腔内大出血等严重并发症。结论 EUS-FNA诊断胰腺癌具有良好价值,且安全性良好。

Objective To investigate the clinical characteristics of pancreatic carcinoma and the diagnostic value of endoscopic ultrasound fine needle aspiration (EUS-FNA)in patients with pancreatic carcinoma.Methods The clinical features and EUS-FNA pathology results of 68 patients with pancreatic carcinoma confirmed by surgery and pathology from September 2011 to Match 201 3 were analyzed.Results There were 47 males and 21 females with the age ranging from 42 to 82 years.The tumor diameter ranged from 11 to 42 mm.Twenty-one (31 %,21 /68)cases located in pancreatic head,12 (1 8%,12 /68)in pancreatic neck,17 (25%,17 /68)in pancreatic body,1 8 (26%,1 8 /68)in pancreatic tail.The sensitivity,specificity and positive predictive value of EUS-FNA were 88%,100% and 100% respectively.The positive rates of histopathology and cytopathology were 84% (57 /68)and 38% (26 /68).EUS-FNA was conducted on all 68 patients without any serious complications,such as acute pancreatitis,pancreatic infection,intra-abdominal bleeding.Conclusion EUS-FNA is an effective and safe procedure in histopathologic diagnosis of pancreatic carcinoma.