ICU特异性干预对感染性休克的干预效果

Effect of ICU-specific intervention on patients with septic shock

目的研究重症监护病房(ICU)特异性干预对感染性休克患者心功能及炎性因子的影响,为感染性休克疾病治疗提供参考。方法选取2014年3月-2017年3月医院收治的感染性休克患者225例为研究对象,随机分为研究组113例和对照组112例,对照组常规干预,研究组在常规干预基础下行特殊干预,观察记录两组患者干预前后血清C-反应蛋白(CRP)、心率(HR)、心脏指数(CI)、平均血压(MAP)、静脉血氧饱和度(SVO2)、住院时间和住院费用等指标的变化情况及两组疗效情况。结果研究组疗效优于对照组(P=0.005);干预后研究组和对照组血清CRP分别为(5.21±1.02)、(7.39±1.56) mg/L,MAP分别为(69.58±12.84)(74.26±15.01)mmHg,SVO2分别为(71.25±7.35)、(65.32±9.21)%,差异均有统计学意义(P<0.05);研究组和对照组患者住院时间分别为(7.63±1.28)、(12.96±3.75)d,住院费用分别为(15 637.95±36.85)、(29 867.34±86.99)元,差异有统计学意义(P<0.05)。结论 ICU特异性干预可提升感染性休克患者心功能指标,临床治疗效果好,缩短患者住院时间,降低患者住院费用,具有一定的临床价值。

OBJECTIVE To study the effect of ICU-specific intervention on cardiac function and inflammatory factors in patients with septic shock,and provide reference for the treatment of septic shock disease.METHODS A total of 225 patients with septic shock admitted to the hospital from Mar.2014 to Mar.2017 were enrolled.They were randomly divided into the study group(113 cases)and the control group(112 cases).The control group received routine intervention.The study group underwent special intervention in addition to routine intervention.The changes of serum C-reactive protein(CRP),heart rate(HR),cardiac index(CI),mean blood pressure(MAP),venous oxygen saturation(SVO2),hospitalization time and hospitalization expenses before and after intervention as well as the curative effect in the two groups were observed and recorded.RESULTS The curative effect of the study group was better than that of the control group(P=0.005);after the intervention and control groups were serum CRP(5.21±1.02)is,(7.39±1.56)mg/L,MAP,respectively(69.58±12.84)(74.26±15.01)mmHg is,SVO2 respectively(71.25±7.35),(65.32±9.21)%,the difference was statistically significant(P<0.05);Study group and the control group patients were hospital stay(7.63±1.28),(12.96±3.75)d,respectively,hospitalization costs(15 637.95±36.85),(29 867.34±86.99)element,the difference was statistically significant(P<0.05).CONCLUSION ICU-specific intervention can improve the cardiac function index of patients with septic shock,and the clinical treatment effect is good.It shortens the hospitalization time of patients,reduces the hospitalization cost of patients,and has certain clinical value.