阻塞性睡眠呼吸暂停综合征与不同体位下鼻阻力的关系

The study of the relationship between obstructive sleep apnea syndrome and positional nasal resistance

目的 :探讨不同体位下鼻阻力的变化及其与阻塞性睡眠呼吸暂停综合征 (OSAS)的关系。方法 :对 14例正常人、2 0例单纯鼾症和 4 0例OSAS患者进行坐位和仰卧位的鼻阻力检测 ,并行多导睡眠呼吸监测。将单纯鼾症和OSAS患者按有无鼻腔疾病分成阴性组和阳性组。结果 :①单纯鼾症鼻阴性组以及OSAS鼻阴性组的鼻阻力明显高于正常组 (P <0 .0 5 )。②OSAS鼻阳性组坐位与卧位鼻阻力明显高于单纯鼾症鼻阳性组 (P <0 .0 5 )。③各分组卧位的鼻阻力高于坐位(P <0 .0 5 ) ,OSAS鼻阴性组和阳性组之间差异有极显著性意义 (P <0 .0 1)。④OSAS患者中 ,鼻阳性组呼吸暂停和低通气指数、觉醒指数、鼾声指数高于鼻阴性组 ,最低血氧饱和度低于鼻阴性组 (P <0 .0 5 )。结论 :单纯鼾症与OSAS患者鼻阻力都较正常人增加 ,且仰卧位时较坐位时明显增加 ;

Objective:To study the nasal resistance in different position and its possible relationship to obstructive sleep apnea syndrome (OSAS).Method:The positional rhinomanometry and the detection of polysomnography were performed in 14 normal subjects,20 snoring patients and 40 patients with OSAS.Result:The study reveals that:①the nasal resistance in seated position and in supine position of the patients with OSAS but without nasal diseases or snoring patients without nasal disease were higher than that of the normal group(P< 0.05 ).②The nasal resistance in seated position and in supine position of the patients with both OSAS and nasal disease were higher than that of the snoring patients with nasal disease(P< 0.05 ).③The nasal resistance in supine position was higher than the nasal resistance in seated position in all the groups(P< 0.05 ),even in the the patients with OSAS(P< 0.01 ).④The AHI?waken intervals?snoring index of the patients both with OSAS and nasal disease were higher than those of the patients only with OSAS.Conclusion:Nasal resistance increased in the patients with snoring or OSAS and increased more in the supine position.Nasal resistance may be an important factor in the pathogenesis of OSAS.