鼾症与脑梗死的关系研究

A epidemiologic study for relation between the snore and cerebral infarction

目的 :探讨单纯型鼾症、憋气型鼾症和脑梗死的关系。方法 :脑梗死组 6 0例和正常对照组 6 0例 ,排除年龄、性别、肥胖等因素的影响 ,进行控制配比的析因研究。结果 :鼾症者较无鼾症者脑梗死的发生几率稍有增加 ,统计学分析差异无显著性意义。单纯型鼾症较无鼾症者 ,脑梗死的发生几率接近 ,差异无显著性意义。憋气型鼾症与单纯型鼾症比较 ,脑梗死的相对危险度明显增加 ,有统计学意义 (P <0 .0 5 )。憋气型鼾症与无鼾症者比较 ,脑梗死的相对危险度最高 ,差异有极显著性意义 (P <0 .0 1)。结论 :鼾症是脑梗死的可能原因之一 ,鼾症特别是有呼吸暂停的憋气型鼾症发生脑梗死的可能性大于无鼾症者。

Objective:To explore the relation between cerebral infarction and simple,apneic snore. Method:A case control comparative study with the exception of influencing factors such as ages, sex, obesity and so on in 60 patients with cerebral infarction and 60 control subjects. Result:The probability of cerebral infarction is a little high in all snorer compared with the no snorer. The Odds ratio is 1.709 (95% confidence limits 0.798 ～ 3.705 ). The probability persist high in apneic snore compared with other kind of snore. The Odds ratio is 3.571 (95% CL 1.295 ～ 9.849 , P< 0.05 ). The Odds ratio of cerebral infarction is highest in apneic snore compared with normal subjects ( Odd ratio= 4.107 , 95%CL 1.407 ～ 11.99 ,P< 0.01 ). Conclusion:Cerebral infarction is not obviously related with common snore, It is related significantly with the apneic snore. It indicated that snore is a possible cause of cerebral infartion. The possibility suffering from cerebral infarction is more in people especially in apneic snorer than no snorer.