纳络酮治疗急性酒精中毒113例临床观察

An Observation of the Clinical Effect of Naloxone in the Treatmentof 113 Cases of Acute Alcoholism

目的 探讨纳络酮对急性酒精中毒的治疗效果 方法 将113例急性酒精中毒患者随机分成两组,其中60例采用纳络酮治疗,53例采用常规治疗,对比其临床疗效、神志清醒时间、病死率等情况 结果 治疗组与对照组神志清醒时间比较具有显著性差异(p<0 01),治疗组无死亡病例,对照组死亡1例 结论 纳络酮治疗急性酒精中毒安全性高,疗效好,催醒快,毒副作用小。

OBJECTIVE: To observe the clinical effect of Naloxone in the treatment of acute alcoholism. METHOD: Total 113 cases divided into two groups at random, 60 cases treated with Naloxone and other 53 cases with routine method. The clinical effect, the time of the recovery of consciousness and the death rate were observed and analyzed. RESULT: The time of recovery of consciousness was shorter in the Naloxone group significantly(p<0.01). There was no death in the Naloxone group and one death in the control group. CONCLUSIONS: Naloxone is a safe, effective drug with less side effect in the treatment of acute alcoholism, so it may be selected as a first line drug.