检查前未大量饮水对骨显像图像质量的影响

Evaluation of the effects of non-hydration on the quality of bone scan

目的:探讨未专门饮水对骨显像图像质量的影响,以及该方法在临床应用的可行性和采集图像的最佳时间。方法:将32例患者随机分为大量饮水组(饮水组)和未大量饮水组(未饮水组),每组16例;饮水组注药后饮水1000ml以上,未饮水组注药后正常饮食;两组均于注药后3小时开始行全身前位和后位骨显像,未饮水组注药后4、5小时再各完成1次全身后位骨显像;用目测和半定量分析判断图像结果。结果:饮水组和未饮水组注药后3小时图像质量的差别无显著意义;未饮水组注药后3、4、5小时目测图像质量无明显差别,但半定量分析表明,随时间的推移,骨与软组织的放射性比值有所增加。结论:骨显像时患者不大量饮水是可行的,特别适于不能大量饮水和排尿困难的患者;未饮水组采集图像的最佳时间后延,注药后4小时为宜。

Objective: To evaluate the effects of non-hydration on the quality of bone scan. Materials and Methods: There were 32 patients divided randomly and equally into two groups: group hydration (group H) and group non-hydration (group NH). Patients in group H drank fluid more than 1000ml after injection of 99mTcm-MDP in 2 hours, while patients in group NH just had routine lunch without special fluid intake. Bone scans in both groups were performed at 3 hours after injection of 99Tcm-MDP and in group NH additional scans were acquired at 4 and 5 hours after injection. Images were compared by visual and semi-quantitative analyses. Results: There was no significant difference of the image quality between group H and group NH at 3 hours. There was no significant difference among the image qualities at 3, 4 and 5 hours, visually. However, by the semi-quantitative analyses, the bone/soft tissue radioactivity ratios were gradually increased by time delayed. Conclusion: Non-hydration is feasible to have bone scan, which is specially fit to patients who are not able to drink a lot of fluid and with dysuria. The optimum time for the acquisition of bone scan is at 4 hours often injection of 99Tcm-MDP in non-hydration patients.