利用转基因植物制备S-IgA的研究进展

Research development about production of secretory IgA antibodies in plant

S -IgA作为口腔防御系统的第一道屏障 ,在龋病防治方面具有重要作用。利用转基因植物生产抗体可较好地解决S -IgA大规模的生产和应用问题。本文就转基因植物表达系统的特点 ,抗体生产中所涉及的问题及S

Secretory IgA(S-IgA) provides the first l ine of immune defense at the mucosal surface. It plays a critical role in provid ing protection against human dental caries.The problem about large-scale product ion and application of S-IgA can be resolved by transgenic plant biotechnology. This article is summarizing the recent studies on the traits of transgenic plant expression system and issues regarding plantibody production and development of secretory IgA.