摘要
目的总结虾青素对肿瘤的预防和治疗作用,归纳其作用机制。方法回顾近年来国内外发表的有关虾青素和肿瘤的中、英文文献并进行综合评述。结果虾青素有很强的抗氧化作用。虾青素能够预防肿瘤的发生,抑制肿瘤细胞增殖,促进凋亡,抑制转移,增强免疫,调节细胞通讯等发挥抗肿瘤作用。结论虾青素有一定的抑癌、抗癌作用,但其具体机制尚需进一步研究,临床应用尚需大规模前瞻性临床试验的结果。
Objective To summarize the antitumor effect of astaxanthin and its mechanism.Methods We collected and analysed the results from articles related to astaxanthin and tumor.Results astaxanthin have a strong antioxidant effect. and astaxanthin can prevent cancer, inhibit tumor cell proliferation, promote apoptosis, inhibiting metastasis, enhance immunity, regulating cell communication to achieve antitumor effect.Conclusions Astaxanthin has antitumor effect, but the specific mechanism is still unclear. The clinical application of astaxanthin warrants large-scale prospective clinical trials.
出处
《肿瘤代谢与营养电子杂志》
2015年第4期58-62,共5页
Electronic Journal of Metabolism and Nutrition of Cancer
基金
上海市卫生局科研课题(20124428)
上海交通大学多学科交叉项目培育(医工)基金(YG2012MS26)
