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肿瘤放射治疗中MnSOD的生物学效应及治疗作用研究进展 被引量：1

Progress of Biological and Therapeutic Effect of Manganese Superoxide Dismutase in Tumor Radiotherapy
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摘要 Mn SOD是一个定位于线粒体基质中主要的抗氧化酶,在肿瘤的发生、发展和肿瘤放射治疗中的辐射保护、放疗增敏等方面有着重要的作用。调控Mn SOD在正常组织和肿瘤组织中的表达有望成为肿瘤临床放射治疗的重要靶点。 Manganese superoxide dismutase(Mn SOD), which is located in the mitochondrial matrix, is an important antioxidase to eliminate reactive oxygen species within the cells. The regulation of Mn SOD expression within normal and tumor tissues would be an important therapeutic target for radiation oncology, since Mn SOD plays an important role in oncogenesis, tumor progression, radiation protection, and radiosensitivity.
作者 张志强 王卫东
机构地区 重庆医科大学附属儿童医院急诊科 四川省肿瘤医院放疗中心
出处 《肿瘤防治研究》 CAS CSCD 北大核心 2015年第8期839-842,共4页 Cancer Research on Prevention and Treatment
基金 国家自然科学基金(11375124) 四川省自然科学基金(2013JY0106)
关键词 锰超氧化物歧化酶 肿瘤 放射治疗 Manganese superoxide dismutase(Mn SOD) Tumor Radiotherapy
分类号 R730.55 [医药卫生—肿瘤]
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参考文献21

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二级参考文献20

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肿瘤防治研究
2015年 第8期

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