声门型喉癌低温等离子射频消融术治疗后局部复发与前联合受侵犯的关系

Relationship between Local Recurrence and Anterior Commissure Involvement in Early Glottic Laryngocarcinoma after Radiofrequency Coblation

目的分析低温等离子射频消融术治疗声门型喉癌局部复发与前联合受侵犯的关系。方法回顾性分析2008年6月—2013年10月于我科低温等离子射频消融术治疗的73例早期声门型喉癌患者资料。其中病变侵犯前联合组25例,病变未侵犯前联合组48例。术后随访18~82月。比较病变侵犯前联合组与未侵犯前联合组的局部复发率。结果 3例低温等离子射频消融术术后死亡4例,局部复发率15.07%(11/73)。其中Tis局部无复发;T1a复发率为8.33%(3/36)、T1b为41.67%(5/12)、T2为33.33%(3/9)。病变侵犯前联合组复发率36%(9/25);病变未侵犯前联合组复发率4.17%(2/48),两组之间差异有统计学意义(P=0.001)。结论低温等离子射频消融术治疗侵犯前联合的早期声门型喉癌复发率高,其治疗价值值得进一步研究。

Objective To analyze the relationship between local recurrence and anterior commissure involvement in early glottic laryngocarcinoma after radiofrequency coblation. Methods We retrospectively reviewed the data of 73 early glottic laryngocarcinoma patients treated with radiofrequency coblation from June 2008 to October 2013, including 25 cases with anterior commissure involvement and the other 48 cases without. The follow-up period ranged from 18 to 82 months. The local recurrence rate between the involvement and non-involvement of anterior commissure was compared. Results Local recurrence were detected in the 73 cases with early glottic laryngocarcinoma after radiofrequency coblation, 4 cases died and local recurrence was found in 11 cases. The local recurrence rate was 15.07%(11/73). The recurrence rates of Tis, T1 a, T1 b and T2 were 0%, 8.33%(3/36), 41.67%(5/12) and 33.33%(3/9), respectively. In 25 cases with anterior commissure involvement, the local recurrence rate was 36%(9/25). In 48 cases without anterior commissure involvement, the local recurrence rate was 4.17%(2/48). Significant differences were found between the two groups(P<0.05). Conclusion After radiofrequency coblation on early glottic laryngocarcinoma patients, a higher recurrence rate is found in the lesions with anterior commissure involvement, which still needs further research.