术前Hook-wire导丝定位的肺部磨玻璃结节临床病理特征分析

The postoperative clinicopathological characteristic of ground glass opacity localized by Hook-wire

目的评价术前Hook-wire导丝定位的肺部磨玻璃结节(ground glass opacity,GGO)临床、影像特征与病理的关系。方法收集83例GGO患者的临床、影像与术后病理资料,分析单纯磨玻璃病变(pure ground glass opacity,pGGO)与混合磨玻璃病变(mixed ground glass opacity,mGGO)的临床、影像特征与病理之间的联系。结果 83个病灶(pGGO 36例,mGGO 47例)均导丝定位成功,无严重并发症发生。对比分析发现mGGO中浸润性腺癌(IAC)患者比例明显高于pGGO(21.7%vs 7.2%,P=0.004);而且mGGO组直径大于1 cm者IAC患者比例明显高于直径小于1 cm者(29.8%vs 8.4%,P=0.003);年龄、性别、位置分布与病理类型无明显差别。结论 mGGO中IAC患者比例明显高于pGGO;结节直径≥cm的mGGO患者需采取积极的治疗方案。

Objective To evaluate the relationship between the clinical and imaging features of the postoperative clinicpathological characteristic of ground glass opacity(GGO)localized by Hook-wire.Methods Retrospective analysis was made in 83 cases of GGO patients with a diameter less than 2 cm in clinical data,imaging data and postoperative pathology,analysis of imaging findings of pure ground glass opacity(pGGO)and mixed ground glass opacity(mGGO).The relationship between clinical,imaging features and postoperative pathology of GGO was analyzed.Results A total of 83 lesions(36 cases of pGGO and47 cases of mGGO)were successfully localized by Hook-wire with no severe complications.Comparative analysis found that the proportion of patients with invasive adenocarcinoma(IAC)in mGGO was significantly higher than that of pGGO(21.7%vs 7.2%,P=0.004).The proportion of IAC patients with diameter greater than 1 cm in mGGO group was significantly higher than that with diameter less than 1 cm(29.8%vs 8.4%,P=0.003).There was no significant difference in age,gender,location distribution and pathological type.Conclusion The proportion of IAC patients in mGGO is significantly higher than that of pGGO.mGGO patients with opacity diameter≥1.0 cm need to adopt active therapeutic plan.