血糖与冠状动脉介入治疗后造影剂肾病的相关性

Correlation of glucose and contrast-induced nephropathy after percutaneous coronary intervention treatment

目的探讨血糖水平与冠状动脉介入治疗后造影剂肾病发生的相关性。方法选择行冠状动脉造影术及冠状动脉支架植入术的患者230例,均应用低渗非离子型造影剂碘海醇进行造影,按照血糖指标分为非糖尿病(DM)组(n=112)、糖耐量异常组(n=38)、DM组(n=80),分析三组治疗后平均血尿素氮、血肌酐值及照影剂肾病的发生率。结果三组血尿素氮、血肌酐值比较,糖耐量异常组高于非糖尿病组(P<0.05),DM组显著高于糖耐量异常组(P<0.01)。非DM组造影剂肾病发生率为2.7%,糖耐量异常组为5.3%,DM组为8.8%。结论血糖水平与冠状动脉介入治疗后造影剂肾病发生呈正相关,对糖尿病及糖耐量异常患者,在行冠状动脉介入检查及治疗时,应注意预防造影剂肾病的发生。

Objective To analyze the correlation between blood glucose levels and coronary intervention after the occurrence of con -trast induced nephropathy.Methods 230 patients were divided into non-diabetic (n=112),abnormal glucose tolerance (n=38),diabetic groups (n=80) according to the glycemic index.The average incidence of blood urea nitrogen and serum creatinine values and lighting con -trast agent nephropathy were analyzed .Results The levels of blood urea nitrogen and serum creatinine values were higher in abnormal glu -cose tolerance group than those of non-diabetic group(P<0.05),were higher in diabetes group than those of abnormal glucose tolerance group (P<0.01).The incidence of contrast-induced nephropathy in non-diabetic nephropathy group was 2.7%,5.3%in abnormal glucose toler-ance,and 8.8% of diabetic group .Conclusions Blood glucose levels after percutaneous coronary intervention with contrast -induced ne-phropathy occurred positively correlated when diabetes and impaired glucose tolerance , coronary interventional examination and treatment should be taken to prevent the occurrence of contrast-induced nephropathy .