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血管性抑郁发病机制 被引量：6

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摘要 血管性抑郁(VD)是危害严重的晚发性血管障碍性抑郁症。Gonzalez等〔1〕横断面数据分析表明VD的流行率约为3.4%。而抑郁与心脑血管疾病互为因果致病,明显增加了患者的致残率和死亡率。由于VD患者对目前抗抑郁剂敏感性低(疗效不足50%),耐受性差,易出现毒副作用,对患者及其家庭、社会造成沉重负担,已成为国内外医学关注热点。1致病因素1.
作者 黄世敬 张颖 陈宇霞
机构地区 中国中医科学院广安门医院中药研发中心
出处 《中国老年学杂志》 CAS CSCD 北大核心 2014年第17期5008-5011,共4页 Chinese Journal of Gerontology
基金 国家自然科学基金面上项目(No.30672696 81072801) 北京市自然科学基金项目(No.7093129) 北京市中医管理局项目(No.JJ2011-84)
关键词 血管性抑郁 发病机制 研究进展
分类号 R749.4 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献8

  • 1Raghupathy Paranthaman,Alistair S. Burns,J. Kennedy Cruickshank,Alan Jackson,Marietta L. J. Scott,Robert C. Baldwin.Age at Onset and Vascular Pathology in Late-Life Depression[J].American Journal of Geriatric Psychiatry.2012(6)
  • 2Deanna M. Barch,Gina D?Angelo,Carl Pieper,Consuelo H. Wilkins,Kathleen Welsh-Bohmer,Warren Taylor,Keith S. Garcia,Kenneth Gersing,P. Murali Doraiswamy,Yvette I. Sheline.Cognitive Improvement Following Treatment in Late-Life Depression: Relationship to Vascular Risk and Age of Onset[J].American Journal of Geriatric Psychiatry.2012(8)
  • 3Sean J. Colloby,Michael J. Firbank,Alan J. Thomas,Akshya Vasudev,Steve W. Parry,John T. O’Brien.White matter changes in late-life depression: A diffusion tensor imaging study[J].Journal of Affective Disorders.2011(1)
  • 4R moretti,Luisa de Angelis,Antonello Rodolfo,Paola Torre,Esposito Francesca,Elena Bernobich,Giuseppe Bellini.Depression in vascular pathologies: the neurologist’s point of view[J].Vascular Health and Risk Management (default).2011(default)
  • 5Hendrika J.Luijendijk,HenningTiemeier,Julia F.Van Den Berg,Gysèle S.Bleumink,AlbertHofman,Bruno H.C.Stricker.Heart Failure and Incident Late‐Life Depression[J].Journal of the American Geriatrics Society.2010(8)
  • 6Neil M. Fournier,Ronald S. Duman.Role of vascular endothelial growth factor in adult hippocampal neurogenesis: Implications for the pathophysiology and treatment of depression[J].Behavioural Brain Research.2011(2)
  • 7M. Kamran Ikram,Hendrika J. Luijendijk,Albert Hofman,Paulus T.V.M. de Jong,Monique M.B. Breteler,Johannes R. Vingerling,Henning Tiemeier.Retinal Vascular Calibers and Risk of Late-Life Depression: The Rotterdam Study[J].American Journal of Geriatric Psychiatry.2010(5)
  • 8龙吟,杨婷婷,孙中武.皮质下缺血性抑郁患者血管危险因素与认知损害[J].中华医学杂志,2012,92(5):307-311. 被引量：3

二级参考文献16

  • 1Krishnan KR, Taylor WD, McQuoid DR, et al. Clinical characteristics of magnetic resonance imaging-defined subcortical ischemic depression.Biol Psychiatry,2004,55:390-397.
  • 2Taylor WD,Steffens DC,Krishnan KR.Psychiatric disease in the twenty-first century:the case for subcortical ischemic depression.Biol Psychiatry,2006,60:1299-1303.
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同被引文献58

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二级引证文献38

中国老年学杂志
2014年 第17期

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