期刊文献+

强化型匀浆膳治疗老年心衰合并肾衰患者的疗效 被引量:6

下载PDF
导出
摘要 目的观察强化匀浆膳治疗对心衰合并肾衰老年患者的营养状况以及心功能、肾功能的影响。方法心功能不全合并肾功能不全的危重症老年病例96例,分为个性化营养治疗组(试验组,52例)和整蛋白型肠内营养制剂治疗组(对照组,44例),经NRS2002筛查,全部病例均存在营养不良风险;待病人生命体征平稳,给予不同方案肠内营养治疗,密切观察胃肠道反应,并分别于治疗初始、治疗7 d及治疗14 d采集静脉血,测定白蛋白、前白蛋白、总蛋白、肌酐、尿素氮、B型钠尿肽(BNP)等指标,评价治疗效果。结果试验组患者对个性化匀浆膳的耐受性较好,无不良反应发生,对照组有4例发生腹泻;试验组前白蛋白水平在干预后7 d有升高趋势,14 d后明显升高,与治疗开始及对照组比较具有显著差异(P<0.05);其余营养学指标实验期间变化不显著;实验组肌酐水平在治疗后7 d即明显下降(P<0.05),治疗后14 d下降更为显著,且明显低于对照组(P<0.05);对照组尿素氮水平在治疗7 d及14 d均显著高于治疗初始,而试验组没有显著变化。与治疗开始时比较能够两组BNP水平均明显下降(P<0.05及P<0.01),14 d时实验组BNP水平显著低于对照组(P<0.05)。结论个体化高能量低蛋白型营养治疗方案在一定程度上能够改善心衰合并肾衰的老年患者蛋白代谢状况,减轻重要脏器负担,延缓病情进展;对多器官衰竭的病人分析其具体营养需求,采用个体化的营养支持将更有利于良好的临床转归。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第3期587-589,590,共4页 Chinese Journal of Gerontology
  • 相关文献

参考文献11

  • 1Fiaccadori Enrico,Parenti Elisabetta,Maggiore Umberto.Nutritional support in acute kidney injury. Journal de Neuroradiologie . 2008
  • 2Mo Yeon Hwa,Rhee Jinnie,Lee Eui-Kyung.Effects of nutrition support team services on outcomes in ICU patients. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan . 2011
  • 3Jiménez Jiménez FJ,Cervera Montes M,Blesa Malpica AL.Guidelines for specialized nutritional and metabolic support inthe critically-ill patient:update.Consensus SEMICYUC-SENPE:cardiac patient. Nutricion Hospitalaria . 2011
  • 4Milovanov Iu S,Lysenko L V,Milovanova L Iu,Dobrosmyslov I A.[The role of balanced low-protein diet in inhibition of predialysis chronic kidney disease progression in patients with systemic diseases]. Terapevticheski? arkhiv . 2009
  • 5Sánchez C,Aranda P,Planells E,Galindo P,Pérez de la Cruz A,Larrubia M,Llopis J.Influence of low-protein dietetic foods consumption on quality of life and levels of B vitamins and homocysteine in patients with chronic renal failure. Nutrición hospitalaria : organo oficial de la Sociedad Espa?ola de Nutrición Parenteral y Enteral . 2010
  • 6Chazot Charles,Jean Guillaume,Vo-Van Cyril,Collonge Cecile,Terrat Jean Claude,Vanel Thierry,Lorriaux Christie,Hurot Jean Marc,Charra Bernard.The plasma level of brain natriuretic peptide is increased in malnourished hemodialysis patients. Blood Purification . 2009
  • 7F. Blondé-Cynober,G. Morineau,B. Estrugo,E. Fillie,C. Aussel,J.-P. Vincent.Diagnostic and prognostic value of brain natriuretic peptide (BNP) concentrations in very elderly heart disease patients: Specific geriatric cut-off and impacts of age, gender, renal dysfunction, and nutritional status[J]. Archives of Gerontology and Geriatrics . 2010 (1)
  • 8Jane M. Gervasio,Ann B. Cotton.Nutrition support therapy in acute kidney injury: Distinguishing dogma from good practice[J]. Current Gastroenterology Reports . 2009 (4)
  • 9Mette M. Berger,Jean-Pierre Revelly,Marie-Christine Cayeux,René L. Chiolero.Enteral nutrition in critically ill patients with severe hemodynamic failure after cardiopulmonary bypass[J]. Clinical Nutrition . 2004 (1)
  • 10Carlo Meloni,Paola Tatangelo,Silvia Cipriani,Valeria Rossi,Concetta Suraci,Carmela Tozzo,Bernardo Rossini,Annalisa Cecilia,Damiano Di Franco,Emilia Straccialano,Carlo U. Casciani.Adequate protein dietary restriction in diabetic and nondiabetic patients with chronic renal failure[J]. Journal of Renal Nutrition . 2004 (4)

二级参考文献17

  • 1Nash K, Hafeez A, Hou S. Hospital-acquired renal insufficiency.Am J Kidney Dis,2002,39:930-936.
  • 2Schiffl H,Lang SM,Fishcher R.Daily hemodialysis and the outcome of acute renal failure.N Eng J Med,2002,346:305-310.
  • 3Levy EM,Viscoli CM,Horwitz RI.The effect of acute renal failure on mortality.A cohort analysis.JAMA,1996,275:1489-1494.
  • 4Chertow GM,Lazars JM,Paganini EP,et al.Predictors of mortality and the provision of dialysis in patients with acute tubular necrosis. The Auriculin Anaritide Acute Renal Failure Study Group.J Am Soc Nephrol,1998,9:692-698.
  • 5Brivet FG,Kleinknecht DJ,Loirat P,et al.Acute renal failure in intensive care units-Causes, outcome, and prognostic factors of hospital mortality: A prospective,multicenter study.French study group on acute renal failure.Crit Care Med,1996,24:192-198.
  • 6Chertow GM, Goldstein-Fuchs DJ, Lazarus JM, et al.Prealbumiu,mortality,and cause-specific hospitalization in hemodialysis patients.Kidney Int,2005,68:2794-2800.
  • 7Bellomo R,Ronco C,Kellum JA,et al.Acute Dialysis Quality Initiative Workgroup.Acute renal failure-definition,outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group.Crit Care,2004,8:R204-R212.
  • 8Fiaccadori E,Lombardi M,Leonardi S,et al.Prevalence and clinical outcome associated with preexisting malnutrition in acute renal failure:a prospective cohort study.J Am Soc Nephrol,1999,10:581-593.
  • 9Fouque D,Kalantar-Zadeh K,Kopple J,et al.A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease.Kidney Int,2008,73:391-398.
  • 10Cano N,Fiaccadori E,Tesinsky P,et at.ESPEN guidelines on enteral nutrition:adult renal failure.Clin Nutr,2006,25:295-310.

共引文献8

同被引文献61

引证文献6

二级引证文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部