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谷草转氨酶和谷丙转氨酶水平与急性期缺血性脑卒中患者短期预后的关系 被引量:5

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摘要 目的探讨血清谷草转氨酶(AST)和谷丙转氨酶(ALT)水平对急性缺血性脑卒中患者短期预后的影响。方法收集319例发病48 h以内的缺血性脑卒中病人,采集入院血标本,测定入院时ALT和AST浓度。对研究对象进行3个月随访,观察死亡或残疾的发生。采用多因素Logistic回归模型分析基线ALT和AST与3个月时死亡或残疾的关系。结果预后良好组的ALT水平显著高于预后不良组(P<0.05),预后良好组的AST平均水平高于预后不良组,但无统计学差异(P>0.05)。但是在年龄<60岁和饮酒的缺血性脑卒中患者中,AST高水平组3个月后不良结局发生危险显著低于AST低水平组(P<0.05)。结论血清中ALT和AST与缺血性脑卒中病人3个月预后相关。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第4期935-937,共3页 Chinese Journal of Gerontology
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