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自体骨髓间充质干细胞动脉和静脉移植治疗急性脑梗死的疗效对比 被引量：5

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摘要 目的探讨系统评价自体骨髓间充质干细胞(BMSCs)动脉移植治疗急性脑梗死(ACI)的疗效和安全性。方法将脑梗死患者112例随机分为干细胞动脉移植组和静脉移植组各56例。两组BMSCs均取自患者本人。动脉组行介入移植术,将BMSCs超选注入脑病变供血动脉。静脉组将BMSCs静脉回输入体内。两组于治疗前、治疗后1个月、3个月监测美国国立卫生医院神经功能缺损(NIHSS)评分。结果动脉移植组治疗后1个月、3个月NIHSS评分显著低于静脉移植组(P<0.05)。两组均无不良反应发生。结论 BMSCs动脉移植和静脉移植治疗脑梗死疗效均显著,安全,动脉移植获益更大。
作者 王旭 张志彬 杨宏 贾芙蓉 张丽艳 荣继平
机构地区 解放军第
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第6期1483-1484,共2页 Chinese Journal of Gerontology
基金 吉林省卫生厅资助项目(No.2009ZC010) 吉林省科委资助项目(No.201105036)
关键词 骨髓间充质干细胞 动脉移植 静脉移植 脑梗死
分类号 R743.33 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献6

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二级参考文献39

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共引文献32

同被引文献45

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引证文献5

二级引证文献2

中国老年学杂志
2015年 第6期

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