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喉癌组织中CD70的表达及其意义

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摘要 目的探讨分化抗原簇70(CD70)在喉鳞状上皮细胞癌(LSCC)组织中的表达。方法利用CD70单克隆抗体,通过免疫组织化学技术对32例LSCC组织和22例正常声带组织标本进行免疫组织染色,探讨CD70在人喉癌组织中的表达。结果全部32例喉癌组织中CD均有表达,阳性率为100%;而在正常声带组织中仅有2例呈弱阳性表达,阳性率仅为9%,差异有统计学意义(P<0.05)。结论 CD70在LSCC中高度表达,可能参与喉癌组织的抗肿瘤免疫活性。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第6期1575-1576,共2页 Chinese Journal of Gerontology
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