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放疗联合化疗治疗局部晚期鼻咽癌的预后对比 被引量:12

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摘要 目的探讨同步放化疗与单一放疗及放疗后辅助化疗对局部晚期鼻咽(LA-NPC)癌患者生存预后的影响。方法 160例经病理学确诊的LA-NPC患者分为三组,其中70例患者采用放射治疗同步联合顺铂及多西他赛化疗,42例仅接受常规放疗,48例接受放疗后再结合顺铂及多西他赛进行辅助化疗,所有患者的TNM分期均为Ⅲ期或Ⅳa、Ⅳb期,治疗后连续随访5年。以治疗后患者的总体生存率、肿瘤远处转移率及复发率评估不同治疗方式的疗效。结果三组的5年总体生存率、5年远处转移生存率、5年复发率,差异均具有统计学意义(P<0.05,P<0.001)。结论同步放化疗治疗较单一放疗及放疗后辅助化疗治疗局部晚期鼻咽癌,可有效阻止疾病的进展及复发,有效提高患者的远期生存率。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第8期2062-2063,共2页 Chinese Journal of Gerontology
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