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肺保护性通气策略联合肺复张治疗严重烧伤伴急性呼吸窘迫综合征的疗效 被引量:5

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摘要 目的探讨肺保护性通气策略联合肺复张治疗严重烧伤并发急性呼吸窘迫综合征(ARDS)患者的临床疗效。方法选择2011年1月至2014年12月在该院收治的严重烧伤并发ARDS患者60例,采用肺保护性通气策略联合肺复张(RM)进行治疗。分别测定联合RM前、RM24 h和RM后患者血气分析指标和血流动力学参数指标,并采用重复测量资料方差分析进行统计学检验。结果联合RM前、RM 24 h和RM后患者p H值和二氧化碳分压(Pa CO2)的总体变化无统计学意义(P>0.05),血氧分压(Pa O2)和氧合指数(OI)的总体变化有统计学意义(P<0.01),RM 24h和RM后Pa O2和OI的值均高于RM前(P<0.01)。患者心率、平均动脉压(MAP)、中心静脉压(CVP)和心排血量(CO)的总体变化无统计学意义(P>0.05),血管外肺水指数(EVLWI)的总体变化有统计学意义(P<0.01),且RM 24 h和RM后EVLWI均低于肺复张前(P<0.01)。结论肺保护性通气策略联合RM治疗能够改善严重烧伤并发ARDS患者的Pa O2和OI,降低EVLWI,是治疗该患者的有效方法。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第15期4318-4319,共2页 Chinese Journal of Gerontology
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