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自噬在肿瘤中的作用 被引量:2

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摘要 自噬不同于凋亡。在自噬过程中,先于核的改变,包括高尔基体、核糖体、内质网等发生降解,但细胞骨架成分(中间丝和微丝)却大部分保存;而典型的凋亡细胞骨架成分在早期即有破坏,且表现为细胞质的固缩和细胞器的保留〔1〕。近年来,越来越多的研究表明自噬参与肿瘤的发生发展和治疗。1自噬的过程自噬过程主要分为3个阶段〔2~4〕:(1)自噬体的初步形成:通常在线粒体和内质网连接部位,
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第15期4404-4406,共3页 Chinese Journal of Gerontology
基金 吉林省科技厅项目(3D512J233428)
关键词 自噬 肿瘤
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